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Quantitative Research Of256-slice Spiral CT In Left Coronary Branch Angle And Diameter

Posted on:2015-03-25Degree:MasterType:Thesis
Country:ChinaCandidate:X J RenFull Text:PDF
GTID:2254330428974402Subject:Medical imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective: Quantitative measurement left anterior descendingbranch(LAD),left circumflex branch(LCX) and right coronary artery (RCA)root segment diameters an left coronary bifurcation angle by256slice spiralCT and provided the normal reference value for clinical diagnosis and stenttherapy of coronary artery disease.Methods: Left coronary artery bifurcation angle, the around1cm rootsegmental diameter and area of LAD, LCX and RCA were measured andanalysis the relationship among left bifurcation angle, the diameter and area ofcoronary artery between age and gender in210patients who underwent256slice spiral CT because of coronary artery disease。The results of256slicespiral CT were compared with that of CAG.Results:①There showed no significant difference in coronarybifurcation angle and diameter between256slice spiral CT and CAG in30patients.②The left bifurcation angle, the diameter and area of LAD,LCX,RCA in male group were significantly larger than those infemale(P<0.05),while there were no significant difference between gender inthe coronary artery diameter and area when standardization combining thepatients height and weight (P>0.05).There also showed no significantdifference in coronary bifurcation angle and diameter among different agegroups (P>0.05).③The left bifurcation’s mean and95%reference range’swere29.53~135.42°, The mean and95%reference range of the normalLAD、LADS、LCX、LCXS、RCA、RCAS when standardization combiningthe patients height and weight were1.12~2.41mm,2.06~9.22mm2;0.95~ 2.07mm,1.82~7.11mm2;1.24~2.70mm,2.39~11.10mm2respectively.Conclusion:256iCT can be objectively evaluated the coronary arterybifurcation angle and diameter. The normal values proposed will play animportant role for the left coronary artery Angle increases and coronary arterystenosis. Objective: To explore the relationship between the coronary arteryplaque formation and left coronary bifurcation angle and proximal leftcoronary artery diameter.Methods:678consecutive cases were prospectively analyzed by256iCT coronary artery angiography, including255cases left coronary arterywithout plaque,141males,114females, with the mean age56.78years±10.65years old, and423cases left coronary artery with plaque,258males,165females, with the mean age57.77years±10.18years old. Left bifurcationangle, coronary artery proximal diameter and area were measured usingmulti-planar reconstruction(MPR) and maximum density projection(MIP) andvolume rendering(VR))technique, and assessed the relationship between leftbifurcation angle, the diameter and area of left proximal coronary artery andcoronary artery atherosclerotic plaque formation.Result: The left coronary artery bifurcation angle and the diameter andarea of proximal left anterior descending branch(LAD),left circumflexbranch(LCX) in the left coronary atherosclerosis group were significantlylarger than that in left coronary artery without plaque group(P<0.01). There were no significant differences in the left bifurcation angle and the diameterand area of proximal left anterior descending branch(LAD) among mildstenosis, moderate stenosis and severe stenosis groups of coronaryatherosclerosis (P>0.05).Conclusion:256iCT could be objectively evaluated the left coronarybifurcation angle and diameter. There were significant relationship betweenthe formation of coronary atherosclerosis and the left bifurcation angle anddiameter, which would be more important clinical value for the diagnosis ofcoronary artery disease and stent treatment. Objective: To explore the relationship between the coronary arteryplaque characteristics and left coronary bifurcation angle and proximal leftcoronary artery diameter by256slice CT.Methods: Retrospectively analyzed256iCT coronary arteryangiography data of387cases, included102cases(60men,42women, the agefrom30years to76years and the mean age is52.10years±9.65) left coronaryartery without plaque and285cases(166men,119women, the age from28years to83years and the mean age is55.65years±10.40) left coronary arterywith plaque. Left bifurcation angle, coronary artery proximal diameter andarea were measured using multi-planar reconstruction(MPR) and maximumdensity projection(MIP) and volume rendering(VR))technique,and analyzethe relationship between left bifurcation angle, the diameter and area of leftproximal coronary artery and coronary artery atherosclerotic plaquecharacteristics. Result: The left bifurcation angle and the diameter and area of proximalleft anterior descending branch(LAD),left circumflex branch(LCX) in theleftcoronary atherosclerosis group were significantly larger than those in leftcoronary artery without plaque group(P<0.05). There were no significantdifference in the left bifurcation angle and the diameter and area ofproximalleft anterior descending branch(LAD)among mild stenosis, moderateand severe stenosis group in coronary atherosclerosis non-calcified group(P<0.05)But the left bifurcation angle, the diameter and area of LAD,LCXin male group were significantly larger than those in female(P<0.05)inmoderate and severe stenosis group.Conclusion:256iCT could objectively evaluate the left coronarybifurcation angle and diameter,the degree of stenosis and coronary arteryplaque characteristics,which would be more important clinical value for thediagnosis of coronary artery disease and treatment. Objective: To explore the relationship between hypertensione and leftcoronary bifurcation angle and proximal left coronary artery diameter by256slice CT.Methods:Retrospectively analyzed256iCT coronary artery angiographydata of160cases left coronary artery without plaque, included80cases(42men,38women, the age from29years to77years and the mean age is55.16years±10.59) the presence of hypertension and80cases(39men,41women, the age from30years to76years and the mean age is52.84years± 10.16) the absence of hypertension. Left bifurcation angle, coronary arteryproximal diameter and area were measured using multi-planarreconstruction(MPR) and maximum density projection(MIP) and volumerendering(VR)technique,and analyze the relationship between left bifurcationangle, the diameter and area of left proximal coronary artery and hypertension.Results:The left bifurcation angle and the diameter and area of proximalleft anterior descending branch(LAD),left circumflex branch(LCX) in the thehypertensive group were significantly larger than those in normalgroup(P<0.05). The longer the course of the disease and hypertension, thehigher the grading, coronary bifurcation Angle and coronary diameter in line.Conclusion:256iCT could be objective evaluation the left coronarybifurcation angle and diameter,determine the early atherosclerosis coronaryartery vascular remodeling in hypertension patients,this topic for coronaryartery disease prevention, diagnosis and further treatment has very importantclinical value.
Keywords/Search Tags:Left coronary bifurcation angle, coronary heartdisease, coronary artery peri-segment diameter and area, computed tomography(CT) imaging, vascular imagingLeft coronary bifurcation angle, coronary atherosclerosis, coronary artery diameter
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