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The Value Of Video-assisted Thoracoscopic Pulmonary Lobectomy And Mediastinal Lymph Node Dissection In The Treatment Of Elderly Patients With Non-small Cell Lung

Posted on:2015-03-26Degree:MasterType:Thesis
Country:ChinaCandidate:Q ZhaoFull Text:PDF
GTID:2254330428985236Subject:Surgery
Abstract/Summary:PDF Full Text Request
Surgical operation is the treatment of non small cell lungcancer (NSCLC) is one of the important means. While the elderlypatients often due to poor cardiopulmonary function of open chestoperation, tolerance of poor, many complications, high mortalityreason to give up the opportunity that the operation treats. Videoassisted thoracoscopic operation (VATS) is minimally invasive,safe, high feasibility, advantages of fast postoperative recovery,less complications. At present, VATS lobectomy and mediastinallymph node dissection has become the treatment of non small celllung cancer (NSCLC) is one of the major operation method of[1-3].Although minimally invasive technology becomes more mature, buit is suitable for aged patients with NSCLC VATS lobectomy andmediastinal lymph node dissection is inconclusive, the operationtrauma, preoperative and postoperative treatment of elderlypatients and non elderly NSCLC patients using video-assistedthoracoscopic lobectomy and mediastinal lymph node by comparing the postoperative recovery, postoperative complicationsand prognosis the situation, to explore the value of this technique inthe treatment of aged patients with NSCLC, to provide thereference for clinical decision making.Results:The two group had statistical significance in patients withunderlying diseases, pulmonary function, the probability of thedifference (P=0.003,0,0.010); the two groups of patients withoperation time, bleeding volume, operation after the chest tubeindwelling time, pleural effusion, the total length of stay afteroperation, analgesic drug use no difference statistical significance(P;>0.05) is greater than or equal to the70groups of patients afteroperation value of cardiovascular morbidity probability and low ratioof less than70years old group (22.7%vs.1.9%, P=0.002);pathology in two cases in this article stage difference was notstatistically significant, with lymph node metastasis in oldernumerical comparison than non elderly patients with low (4.1%vs.8.4%, P=0.142), N1, N2and lymph node metastasis in non elderlygroup values are also low (3.3%vs.83%, vs.8.2%4.6%, P=0.050,0.356); survival analysis showed the1year survival rate in older patients and2year survival rates were96.3%,73.2%,1yearssurvival rate in non elder group patients and2year survival rateswere97.2%,78.4%(P=0.161).Conclusions:Improves with age, basic diseases, patients with higher heartfunction and lung function decline, however, the age is not taboo inthe operation, heart function and pulmonary function evaluation canaccept lobectomy cases, older patients with non small cell lungcancer and age small non-small cell lung cancer patients canaccept operation treatment the prognosis of the patients, andyoung age. To make a long story short, VATS lobectomy andmediastinal lymphadenectomy in the treatment of older patientswith non small cell lung cancer is a feasible and safe way, a goodeffect.
Keywords/Search Tags:Elderly Patients, Lung Cancer, Video-assisted ThoracoscopicSurgery, Lobectomy, Mediastinal Lymph NodeDissection
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