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Comparative Study Of Color Doppler Ultrasound In The Diagnosis Of Breast Cancer And Pathological Results

Posted on:2015-02-05Degree:MasterType:Thesis
Country:ChinaCandidate:D ZhouFull Text:PDF
GTID:2254330428985406Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Objective:High-frequency two-dimensional ultrasound and color doppler ultrasound wasapplied to explore identification of benign and malignant breast masses byretrospective analysis to, and its pathological findings were compared.Methods:Selected April2013-November2013period, female patients made breastsurgery and histopathological examination in second Affiliated Hospital of JilinUniversity. Patients made breast ultrasound examination in preoperative in ourhospital. High-frequency two-dimensional ultrasound was applied to observed breasttumor size, location, shape, border, internal echo and calcification, rear attenuationand axillary lymph node, and CDFI was applied to observed internal mass flowquantity, flow velocity and vascular resistance index. Using the Adler classificationfor grading of blood supply, and tumors were graded to be BIRADS characteristicsaccording to the above described circumstances. These patients were tracked,collected pathological outcomes after operations, which definited benign andmalignant of breast tumor. The resulting ultrasound examinations were compared withpathological results. And compare axillary lymphatic metastasis under ultrasoundwith confirmed pathological axillary lymphatic metastasis. Using χ2test, all thedata were managed by SPSS17.0software. The differences had statistical significanceby P<0.05.On the standard of pathological diagnosis, the ultrasound findings andpathology results organized into four tables from, calculated sensitivity, specificity,positive predictive value, negative predictive value to evaluate the diagnostic value ofultrasound in breast tumor area.Results:Through High-frequency two-dimensional ultrasound and color Doppler ultrasound, benign group of two-dimensional ultrasonography: morphological rules,border clearance, internal echo uniform, no calcification or coarse calcifications, rearwithout attenuation, length/width<1; malignant group of two-dimensionalultrasonography: irregular shape (lobulated, crab foot sign), the border unclear(spiculation), heterogeneous internal echo, the majority of calcification and mainlymicrocalcifications, the part of the nodule rear with attenuation, length/width>1. Intwo-dimensional ultrasound characteristics, shape, boundaries and internal echosensitivity, specificity and accuracy were higher, and specific aspects of the rearattenuation and length/width were the relatively high. Benign tumor blood flow weremore concentrated in the0to1grade, and malignant tumor blood flow were moreconcentrated in the2、3grade, the detection rate of about62.1%.The PSV and RIvalues of the malignant tumor were higher than benign tumor. Detected ultrasoundmedical diagnostic accuracy by BIRADS classification, in the332cases of nodules,most of the benign breast tumors rate of diagnosis is51.4%; most of the malignantbreast tumors rate of diagnosis is95.3%, accuracy was86.4%. A high rate ofmisdiagnosis of benign pathology type was the intraductal papilloma, malignantpathology type was duct carcinoma in situ.Conclusions:High-frequency two-dimensional ultrasound and color doppler imagingtechnology has significant value in differentiating benign and malignant breast tumorareas. Integrated high-frequency two-dimensional ultrasound and color dopplerimaging features, a comprehensive analysis of breast tumor can improve its accuracy.
Keywords/Search Tags:Breast tumor, High-frequency two-dimensional ultrasound, Color dopplerultrasound, Diagnosis, Differential diagnosis
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