Research Of CaP Deposition On Amino Plasma Polymerization Modification Surface In SBF

Based on professor Br nemark’s Osseointegration theory, implant-bone interfacecan form a tight and direct binding, which makes titanium and its alloys has becomethe first choice of oral implants. Titanium and its alloy make implant denture havinghigher chewing efficiency and comfort compared to traditional denture.Prosthodontics by implants are without damage to adjacent teeth, which having beenwidely used in recent years. However, the implantation will take some time to form astable osseointegration, determines the implant denture has a long healing period.Osseointegration of efficiency, quality and implant surface characteristics are closelyrelated, but mainly in the surface characteristics of the implant implant surfacecomposition, roughness, hydrophilicity, etc.. Many scholars conduct research on theimplant-bone interface seeking modifications to shorten the period of restorationplanting, improve the efficiency of implant osseointegration.The current method of implant surfaces treatments are roughen modifications,such as titanium plasma spraying, sand blasting, etching, anodic oxidation. Theroughening treatment or surface roughening treatment by coating get good effects, butthe disadvantages are also obvious. For example, to increase the risks of peri-implantinflammation and ion leakage, micro exfoliation of the coating, insufficient adhesionbetween coating and implant materials and other issues. As researchers attempt to usebiochemical modification of the extracellular matrix, peptides, growth factors. Thesematerials are used in biochemical modification has indeed promoted osteogenesis orbone regeneration effects, but most studies on the biochemical modification in itsinfancy. They are lack of further experimental verification. Therefore, to find a simple,high efficiency, combined with the stability and implant materials to promoteosseointegration exact effect of surface treatment methods are very valuable and necessary.Amino group is one of the most important organic functional groups. It exists inproteins and other biochemical molecules involved in the biochemical reactions inhuman body. Accordingly, the structure and properties of amino group has a highaffinity with cells, tissue. Furthermore, the amino group is often used as the fixed sitesof proteins, enzymes or any other biological macromolecules. Thus, the amino groupmay be introduced to improve the surface of the biocompatible material.As former experiments by Zhao Jinghui, we will continually useplasma-enhanced chemical vapor deposition (PECVD) method, that means forgenerating high frequency discharge plasma cryogenic group, under the conditions ofpolymerization of less than100°C is generated on the metal surface. The surface oftarget material will be modified to produce a homogeneous, stable, polymer film withan amino group on a solid titanium surface. It achieves the purpose of activating thesurface of the material.5set of parameters determined in the previous study (CW,P10%, P30%, P60%, CW+P30%) will be further screened in this subsequentexperiments.The experiment is mainly divided into3parts. First, observe the deposition ofcalcium phosphate salt on the amino plasma modified titanium surfaces after soakedin SBF; Second, qualitative analysis of calcium phosphate salts on amino plasmamodified titanium surfaces; Third, the combination of these experiments, the initialscreening contributes most to implant osseointegration amino plasma surfacetreatment parameters.The results indicates as follows:1,1.5times SBF, soak for24hours, no hydroxyapatite deposition on thesurface of each group; 72hours after immersion, hydroxyapatite deposition on the surface ofgroup1,2,3,5, and group1,2less than group3,5. deposition of each group weremore than the control group; soak for72hours, deposited hydroxyapati te on all thegroups, and no significant difference between the group compared to the controlgroup.2, Group2,3,5have formed hydroxyapatite deposition more quickly whencompared with the rest.This experiment has determined the most favorable parameters of calciumphosphate salt deposition of amino plasma surface modification. Thereby lays thefoundation for the subsequent experiments. The author believes that the follow-upexperiments can be based on the experimental parameters which is most conducive torapid deposition of calcium phosphate salts, with the current clinical-using implantsurface treatment methods for comparison. In vitro and in vivo experiments areneeded for further verification of the promoting effects the amino plasma surfacemodification during osseointegration. This will make contributions to the clinicaluse of the plasma surface modification on titanium implants.