Influencing Factors Of Type2Diabetes Microangiopathy

Objective: To explore the relationship with diabetic microangiopathy, andprovide reference for the prevention and treatment of diabetic microvascularcomplications, detected type2diabetes with blood lipids, blood pressure, bloodsugar and other indicator.Method: Collected256cases from July2012to November2013at the FirstAffiliated Hospital of Guangxi Medical University, Endocrine and MetabolicDiseases inpatient clinical data in patients with type2diabetes, collected gender,age (years), duration (years), smoking history, blood pressure and BMI, fastingblood test for all patients with FBG, PBG, HbA1C, TG, TC, LDL, HDL, UA, CR.After controlling blood sugar steady and continuous stay two days in urine,measured24hours MAU, MAU≥30mg/24h is diabetic nephropathy, excludingother causes of kidney disease. All patients underwent fundus examination andfundus fluorescein angiography after dilation. According to whether microvascular retinopathy or diabetic nephropathy or both, without group was excludedmicrovascular complications of type2diabetes microvascular disease group.Statistical methods using SPSS16.0statistical analysis software to process it, tomeet the normal line of T-test measurement data, measurement data do not meetthe normal row rank sum test, count data using the chi-square test. With or withoutmicrovascular disease as the dependent variable in binary logistic regression,analysising of risk factors for diabetic microangiopathy, with P<0.05wasconsidered statistically significant.Result:1.In this study, diabetic microangiopathy group of117patients andwithout microangiopathy139cases, microangiopathy who had simple diabeticnephropathy, in84cases (32.81%), simple diabetic retinopathy in68patients(26.56%), both diabetic retinopathy and nephropathy disease, in35cases (13.67%).Single factor analysis, comparison in the course, SBP, HbA1C, HDL, LDL, TG,24-hour urinary albumin, CR, UA, smoking history, the difference was statisticallysignificant (P<0.05),gender, age, BMI, DBP, FBG, PBG, TC showed no statisticallysignificant.2.Groups with different duration (<5years,5-10years,>10years) in chi-squaretest, the incidence of diabetic microangiopathy: duration <5years the proportion of31.97%,5-10years, the proportion of53.96%,>10years the proportion of78.26%,was statistically significant between the two groups.3.With or without microvascular disease as the dependent variable in bivariatelogistic regression analysis showed: duration, SBP, UA, smoking history were the risk factors in type2diabetes microvascular disease (P <0.05).Conclusion:1.Type2diabetes microvascular disease of blood sugar, bloodlipids, blood pressure, blood uric acid levels were higher than those withoutmicrovascular disease patients.2. Longer duration, high systolic blood pressure, high uric acid and withsmoking history in patients with type2diabetes, the more microvascular diseaseoccurred.3. Duration, SBP, UA and smoking history could be the risk factors of type2diabetes microvascular disease. Which, SBP, UA may affect the occurrence ofnephropathy more significant, while duration, UA, smoking may affect the diabeticretinopathy more significant.