The Related Factors Of The Establishment Of Collateral Circulation With Symptomatic Internal Carotid Artery System Stenosis And Occlusion

Objective: To explore the related factors of the establishment ofcollateral circulation in patients with symptomatic internal carotid artery systemsevere stenosis and occlusion.Methods: The clinical data of288patients with symptomatic internalcarotid artery system severe stenosis(≥70%) and occlusion were collected andanalyzed retrospectively.The related stroke risk factors for establishment ofcollateral circulation were analyzed by univariate analysis and multinomiallogistic regression analysis.Results: Among the288patients,166had collateral circulation(collateralcirculation group)，and122patients had no collateral circulation(no collateralcirculation group)．Compared with no collateral circulation group，the rate ofhypertension in collateral circulation group was significantly increased（P﹤0.05）, and the Systolic blood pressure on the first day of admission wassignificantly decreased（P﹤0.05）. Also that there were no significant differenceof hypertension among the three lesion segments (extracranial internal carotid artery、intracranial internal carotid artery、middle cerebral artery)with collateralcirculation(P﹥0.05), and there were no significant difference of hypertensionbetween the primary and secondary collateral circulation too(P﹥0.05).Conclusion:1. Multiple ways of collateral circulation can be establishedwhen symptomatic internal carotid artery system severe stenosis or occlusionoccurs in order to alleviate neurologic impairment, and the way of theleptomeningeal anastomose may be the most frequent;2. Hypertension mayplays a promotive role for the establishment of the collateral circulation withsymptomatic internal carotid artery system severe stenosis and occlusion.