Design, Assembly And Performance Of Chiral Ti (Salan) Metal - Organic Frame

Metal-Organic Frameworks, especially for the chiral MOFs show extraordionary application value in following areas such as chiral recognition and separation, chiral catalysis, chiral chemical sensors and gas storage. Among these areas, the application of chiral recognition and separation, chiral catalysis have become the focus of researches by scientists recently. In this paper, pyridyl-functionalized organic linkers based on classic chiral Salan skeletons were synthesized, coordinated with metal ion and utilized to build three kinds of new chiral porous MOF 1, MOF 2 and MOF 3. The structure and properties of these compounds were comfired by a series of techniques including single X-ray diffraction and then catalytic performance were researched. This paper includes the following four chapters:In Chapter 1, we introduce the research background, including the major synthetic methods of MOFs and the application in asymmetric catalysis and chiral recognition and separation. The opportunities, challenges and issues remained in this area were discussed. The design idea, the significance and research progress were discussed and presented in the end.In Chapter 2, a pyridine-functionalized chiral Salan ligand H2L1 was prepared in many steps and then followed by reaction with tetrabutyl titanate to get metalloligand Ti L1. By coordinated with Cd2+ under different thermal solvent condition construst a porous MOF 1 and MOF 2. This material is characterized by XRD, UV, IR and TGA etc. 1 and 2 could serve as an efficient catalyst for asymmetric silylcyanation of aldehydes with high enantioselectivity up to 91%.In Chapter 3, H2L2 and Ti L2 ligands were synthesized through the similar route,then reacted with Cd SO4 and H2 BPDC under different thermal solvent condition to construst MOF 3. Its frame structure was confirmed by the- X-ray single crystal diffraction and infrared spectroscopy and thermogravimetric analysis.In Chapter 4, Comparing with these three MOFs from ligand synthesis to crystalline structure, and explaining the results of asymmetric silylcyanation of aldehydes. A briefly summary and prospect of this thesis were given.