Nanostructured Metal Catalyzed C-C, C-N Cross-coupling Reaction

The nano transition-metal-catalyzed cross-coupling reactions are simple, efficient, and versatile routes to the formation of carbon-carbon bond, carbon-nitrogen bond and so on, which represents the key step in a wide range of preparative organic processes. In recent years, a large number of new transition metal catalysts have been developed by organic workers who are working on new catalytic systems. The contents of this dissertation mainly discussed about two aspects.1. The preparation of nanoparticles, which include magnetically separable Fe3O4/Pd/s-G and Pd nanoparticles. They had smaller size, good catalytic activities, and were prepared by simple wet chemical. After the reaction, they can be separated by simple filtration and recycled conveniently.In addition, they can be reused for several times and still be able to maintain the catalytic activity. Among them, the magnetic nano-particle as a new catalyst has a broad prospect for development. Just using an external field can achieve a simple separation, which is of great significance for the development of green chemistry.2. Magnetically recoverable Fe3O4/Pd/s-G catalyzed C-N bond formation, as well as the Hiyama reaction and Pd hollow nanospheres catalyzed Heck reaction.The details are summarized as follows:1) An efficient magnetically separable Fe3O4/Pd/s-G catalytic system was developed for the regioselective allyl amine reaction. In order to improve the catalytic activity of Pd, PPh3and tetrabutylammonium bromide (TBAB) were used respectively as the ligand and the surfactant in the C-N bond formation reaction. It is indicated that a variety of aromatic and aliphatic amines have been allylated by substituted and unsubstituted allyl acetates efficiently and selectively. This transformation provided the corresponding allylamine with good to excellent yields.2) An efficient magnetically separable Fe3O4/Pd/s-G catalytic system was developed for the Hiyama reaction. The reaction can be carried out in water without the use of phosphine ligands under mild reaction conditions, and affording the corresponding products with good yields.3) Pd hollow nanospheres catalyzed the Heck reaction of the rich electron olefins. The catalyst was used to catalyze the reaction of Iodine Aryl and olefins of rich electron,and we attained the (E)-olefin derivatives.