Electrochemical Method Was Used To Study The Release Of Graphene As A Carrier And The Effect Of Graphene Morphology On Electron Transfer Rate And Electrochemical Luminescence

Graphene’s two-dimensional, highly conjugated, and single atom layered structure endows it with superb thermal electrical, and mechanical properties. Due to these properties, graphene has become one of the most intensely studied materials in the fields of materials science, physics, drug delivery, and nanotechnology. π-π stacking interactions have been extensively utilized to modify carbon allotropes such as graphene and carbon nanotubes because the bonds formed are strong, the modification process is simple to achieve and, of particular importance for nanocarbons, the modification reaction is nondestructive.Herein, we studied the reversibility of π-π stacking interactions at graphite electrodes(GE) of pyrene, 1-aminopyrene, 1-pyrenecarboxylic acid, and doxorubicin hydrochloride(DOX). The interactions between these molecules and graphitic surfaces were investigated by both electrochemistry and theoretical calculations using density functional theory. Experimental studies demonstrated that the charged pyrene derivatives could be electrochemically desorbed from the electrode surface when the same charge was applied on the electrode. In this study, a graphene nanodots-encaged porous gold electrode was prepared to act as working electrode. This kind of porous Au-graphene structure electrode possess more excellent conductivity and graphene specific surface area compared with graphite electrode we used in the previous study.Then, we studied the electron transfer behavior of the graphene modified GCE via direct electrochemical reduction of GO. Electron transfer study using surface immobilized Ru(bpy)32+ as a redox probe revealed that the electron transfer rate constant(Ks) is much faster than that obtained with the GCE modified with tiled graphene. The ECL signal of standing graphene modified Ru(bpy)32+ ECL sensors is much stable and efficient than that of tiled graphene modified one.