The C–S Coupling Reactions Catalyzed By Transition Metals

In recent years, a series of highly efficient reaction systems catalyzed by transition-metals have been developed. Carbon-heteroatom bond forming reactions, especially the formation of C–S bonds greatly improved the appearance of organic chemistry. Aryl sulfide fragments-containing molecules are highly important, the study on C–S bond formation is an important methodology in organic synthesis in view of many decent sulfur-containing natural products. And its application in drug synthesis is of great significance since the sulfur-containing organic compounds products have shown some biological and pharmaceutical activities. Construction of the new C–S bond from a few simple structure sulfur compounds and the application of these newly synthesized compounds become a hot point in organic chemistry in recent years.Secondly, organic porous material could be served as special polymer with excellent properties, for example, high specific surface area, high chemical stability and low density nature. Furthermore, the preparation methods varied, the aperture can be regulated. The property advantages of the organic porous material showed important application potentials. They can be applied in the energy, environment and catalysis aspects, such as hydrogen storage, carbon capture and storage, small organic molecules adsorption, etc.1. An efficient, economical, environmentally friendly and convenient method was developed for the preparation of C–S bond and its applications are showed in this paper. CuCl2 shows good catalytic activity on the reaction starting from iodobezene/TMTD. The corresponding cross-coupling reaction products are obtained with good to excellent yields under relatively mild reaction conditions with good chemoselectivity and functional group tolerance.2. The preparations of phenyl dimethylcarbamodithioate and diaryl sulfide were studied. The former exhibited good to excellent yields, the latter was carried out with phenyl dimethylcarbamodithioate and iodobenzene in DMSO with nickel as catalyst. Mild reactive conditions, commercial available, wide application scope, and shorter reaction times make this method superior to the reported methods for the synthesis of C–S bond containing products.3. In order to study the performance of the organic porous material in terms of gas adsorption, the direct arylation of C–H activation was performed, and the fluorine-containing organic porous polymer was successfully prepared. The specific surface area was 550 m2 g–1, 730 m2 g–1, 820 m2 g–1 and 700 m2 g–1, respectively.