Analysis Of Clinical Features Of141Patients With Hepatic Alveolar Echinococcosis

Objective：To provide necessary theoretical basis and detailed clinic data for thediagnosis, clinic observation and treatment of Hepatic alveolar echinococcosis inepidemic areas by investigating the clinic characteristics of Hepatic alveolarechinococcosis in Qinghai Province and analyzing the relationship between locationof Hepatic Alveolar Echinococcosis (HAE) and each clinic characteristic.Methods：1. Collect clinic cases infected by Hepatic alveolar echinococcosis hospitalizedduring2006and2011(6years) in the three-level hospital in Xining city.2. Divide the collected cases into three groups marked by A,B and C based on theresults of radiographic inspection and hepatic lesions distributing among the leftlobe of liver, the right lobe of liver and both involved.3. To retrospectively analyze the clinic characteristics of three groups’ datamentioned above.Results：Among the141patients infected by Hepatic alveolar echinococcosis, thepatient presented with118cases of right upper quadrant pain,21cases of fatigue andweight loss,13cases of jaundice,64cases abdominal mass and35cases foundduring the examination. The114patients accept the Hydatid IgG antibodyexamination while27patients refuse. As a result, Hydatid IgG antibody in36casesare positive and the positive rate is36/114.39cases are complicated with other organmetastases, of which8cases (20%) are brain metastases,12patients (31%) are lungmetastasis,9patients (23%) are brain and lung metastases,7cases (18%) are brainand kidney metastasis and3cases (8%) are concurrent brain, lung and renalmetastasis. The largest share of organ metastases is lung. All cases accept abdominalCT examination in which98cases are checked by B-mode ultrasonography. B-modeultrasonography, CT and other radiographic inspection have their own characteristic. 87cases of hydatid lesions located in the right lobe of the liver, and23cases in theleft hepatic lobe and about31cases of invasion in the both liver lobes mentionedabove based on the radiographic inspection. The results of three groups mentionedabove account for61.7%,16.3%and22%respectively. The differences of alanineaminotransferase（ALT）among the three groups of the patients have no statisticallysignificance. Statistically significance exist in the diversity of serum total bilirubin（TBIL）, serum albumin（ALB） and the rate of other organ metastases among thethree groups of patients. There is no statistically significance in the divergence oflesion size between the metastasis group and the non-metastasis group.Conclusion： The clinical manifestations of patients with hepatic alveolarechinococcosis are mostly right upper quadrant pain and this is the earliest and mostcommon symptom. The metastasis in extrahepatic organs is significantly higheramong the hydatid lesions in the left liver lobe and both liver lobes than the lesions inthe right liver lobe. When the hydatid lesions are small，the metastasis can alsohappen in extrahepatic organs.