Theanalysis Of Total Parenteral Nutrition Of Neonatal Units

OBJECTIVE：To investigate how Total Parenteral Nutrition(TPN) is applied in the NeonatalUnits of our Hospital, provide further reference to the standardized use of TPN and formulateappropriate guidelines,thus ensure that medicine is properly and safely used. METHODS：Gathered and analyzed the statistics of their prescriptions from2012to June2013, includingsuch things in the Units of TPN as Glucose concentration,the ratios of non-protein calories tonitrogen and carbonydrates to lipids, and the concentration of electrolyte; Appropriategestational age preterm infants(<37weeks)with birth weights <2500g from the patients abovewere assigned into two groups,In Group1(n=27),infants began TPN within3d after birth,andGroup2(n=28) began3d after being born,the body weight were obtained at discharged, thetime to regain birth weigh and biochemical indexes before and after used TPN were alsoobtained. RESULTS：Glucose concentration is controled reasonably, electrolyte concentrationis within the limit,but the prescriptions showed an inappropriateness of the ratios ofcarbonydrates to lipids,and a disproportion of the ratios of non-protein calories to nitrogen; Tocompared with later TPN，early TPN can reduce the time of birth weight gain,and higherTBIL and IBIL,but lower DBIL.There are no differences between the two Groups of the timeof Hospitalization,the time of TPN used,weight growth rate in different time, bloodglucose,K+,Ca2+,Cl-,BUN and serum creatinine.Tow Groups all can prevent and improvehypoglycemia and hypocalcemia,with normal BUN, serum creatinine,TBIL,IBIL and DBIL.CONCLUSION：the prescrition of TPN still needs improving in components.Early TPN canmake better growth of preterm infant.The use of TPN can improve hypoglycemia andhypocalcemia,but have no effect in liver and kidney function.Because nutritional support ofthe two groups are not up to the ideal, it should make further research.