Analysis Of Related Factors Of Chronic Left Ventricular Systolic Dysfunction After Heart Valve Replacement

Objective: With the extracorporeal circulation, myocardial protection, the technology ofthe operation and management of anesthesia improved, which have achieved remarkableprogress, but the cardiac function of some patients after heart valve replacement have notimproved instead of rising down. To improve the quality of life in patients after valvereplacement and further guide clinical work, this paper discusses relevant factors in chronicleft ventricular systolic dysfunction for the patients after heart valve replacement.Methods: We collected data in the medical records room from Union Hospital of FujianMedical University from1January2008to31December2012, and elected normal heartfunction and heart failure group as research subjects. Clinical variables which have beenidentified in the study from the above data may be associated with chronic left ventricularsystolic dysfunction. All the selected clinical variables will be assigned, and then dividedinto categorical variables and continuous variables. Finally Logistic regression analysiswere performed.Results: From the overall level of research, after heart valve replacement factors relatedto left ventricular systolic dysfunction include: preoperative left ventricular end-systolicdiameter (P <0.001), the situation of preservation of mitral apparatus (P=0.043), whetherpreoperative atrial fibrillation (P=0.007), preoperative merger of syncope (P=0.022),whether postoperative use of epinephrine (P=0.032), preoperative ejection fraction (P=0.003);From the type of valve replacement surgery research,after pure mitral valvereplacement factors related to left ventricular systolic dysfunction include: gender (P=0.002), whether left atrial fold over the same period (P=0.013), mitral valve type(domestic or imported)(P=0.003); after pure aortic valve replacement factors related toleft ventricular systolic dysfunction include: preoperative ejection fraction (P <0.001),whether postoperative use of epinephrine (P=0.025), whether postoperative dobutamine (P=0.029), the length of time in ICU(P=0.049). After concomitant mitral and aortic valvereplacement factors related to left ventricular systolic dysfunction include: preoperativeejection fraction (P <0.001).Conclusion: After heart valve replacement factors related to left ventricular systolicdysfunction include: preoperative left ventricular end-systolic diameter, the situation ofpreservation of mitral apparatus, whether preoperative atrial fibrillation, preoperative merger of syncope, whether postoperative use of epinephrine, preoperative ejection fraction.gender, whether left atrial fold over the same period, whether postoperative dobutamine,the length of time in ICU.mitral valve type.