The Comparative Study Of Preoperative Short Course Radiotherapy Combined With Laparoscopic Assisted Operation And Laparoscopic Assisted Operation Alone In The Operation And Postoperative Complications Of Rectal Cancer

Objective:Compared preoperative short course radiotherapy combined withlaparoscopic assisted operation and single laparoscopic assisted operation in rectalcancer operation and postoperative complications,evaluate the influence of thepreoperative short course radiotherapy on operation and postoperative complicationsafter laparoscopic assisted radical surgery.Methods:The clinical data of52patients from gastrointestinal tumor surgery inFujian Province Tumor Hospital from August2012to August2013were collected bythe same surgical operation group of doctors.The patients who suffered locallyadvanced rectal cancer were with stage T3-T4.Among them26cases underwentpreoperative short course radiotherapy combined with laparoscopic assisted operationtreatment (preoperative short course radiotherapy group),26cases of directlaparoscopic assisted operation treatment (the control group).By gender, age, tumorremote from the anal margin, gross type, differentiation degree, preoperative serumCEA, postoperative T staging, N staging after operation, operation time,intraoperative bleeding volume, one by one to control two groups.The two groups ofpatients with tumor operation resection rate, rate of anus preserving and the securityof radical resection of tumor and the difficulty of operation and postoperativecomplications were compared and analyzed.Results:Preoperative short course radiotherapy group and the control group ofpatients rectal cancer operation resection rate was96.2%(25/26) and92.3%(24/26)，Sphincter preservation rate was73.1%(19/26) and61.5%(16/26);Operation time ofshort course preoperative radiotherapy group (126.73±22.78) min, the control groupoperation time is (126.15±25.07) min，There was no significant difference betweenthe two groups(P>0.05);The intraoperative amount of bleeding of short course preoperative radiotherapy group is (145.77±93.73) ml, the amount of bleeding inoperation control group is (141.54±106.98) ml;in preoperative short courseradiotherapy group, the number of positive lymph nodes is (2.42±4.30), control thenumber of positive lymph nodes is (2.58±5.39);preoperative short courseradiotherapy group of lymph node dissection is (23.08±9.70), and in controlgroup,the lymph node dissection is (19.73±10);preoperative short courseradiotherapy group and the control group of patients,the incidence of postoperativecomplications were34.6%(9/26) and26.9%(7/26).The above two groups were notstatistically significant (P>0.05).The differences of the occurrence rate of all kinds ofpostoperative complications were also not statistically significant(P>0.05).The effectof follow-up visit in the near future after operation was well.Conclusions:Combined with laparoscopic assisted operation， preoperative shortcourse radiotherapy does not make the rectal tumor resection rate, radical safety andanal preservation rate decreased.The incidence of the difficulty of operation andpostoperative complications is not increased.In conclusion,it is worthy clinicalapplication.