| Hypertension has caused widespread attention. In the world more than one billion people havehypertension.In China, with a development of socioeconomic, people under non-health life-stylehave a high incidence of hypertension. Among the hypertension people, the rate of awareness ofhypertension was30.2%, the treatment rate was24.7%and the control rate was6.1%. Stroke ismuch more commom than acute myocardial infarction, its annual incidence rate being five timesas high. There was23.1%of deaths caused by myocardial infarction,21.3%caused by stroke;That means hypertension, the major risk factor responsible for the cardiovascular catastrophes,accounts for half deaths in China. Perioprative time it was volatile period for blood pressure, suchas anxiety, induction of anesthesia and the operation technique will cause poor hemodynamiccontrol, and it will has more change in hypertension people. Hypertension will be not controlledwhile the suegeons have little knowledge of hypertension. So to explore the reasonableperioperative treatment for improving the prognosis of patients with high blood pressure is clinicaltask.Objective: To explore the related risk factors of surgery hypertension patients and influence ofprognosis by using different method in perioperative patients with hypertention under generalanesthesia.Method:150elder surgery patients with hypertention in total260patients from the secondaffiliated hospital of Dalian Medical University were selected between June2013andAugust2013, were randomly divided into3groups,50cases in each group. GroupAwere givenisosorbide mononitrate by venous when systolic pressure higher than140mmHg; group B weregiven urapidil by venous when systolic pressure higher than140mmHg; group C perioperativeuse Nifedipine Sustained-release. The highest blood pressure and the lowest blood pressure andthe percent of hypotension were recorded; these adverse events were recorded include hemorrhage,cognitive dysfunction, acute renal failure, myocardial infarction, and shock.Adverse eventswere recorded during the ollow-up survey after surgery for1month,.Result: The risk of occur hypotension was biggest in groupA, Variation of blood pressure ingroup A is the largest. The cases of adverse events were16in group A, and12in group B, whenthere were only5in group C. During follow-up period the cases of adverse events were6in groupA, and4in group B.Conclusion: Age was the most risk factor of hypertension. Perioperative regular use ofantihypertensive agents have better clinical benefit for surgical patients. |