Clinical Epidemiological Characteristics And Prognosis Analysis On208Young Gastric Cancer Patients

Objective：To analyze clinical epidemiological characteristics and prognosticfactors of gastric cancer in young patients and provide reference for clinical treatmentand prognosis.Methods: From January1,2002to December31,2011, a total of208cases inZhengZhou People’s Hospital were retrospectively reviewed and followed up.Log-rank test was used to analyse the prognostic factors.Results: In total of208cases, the young patients were accounted for6.14%ofhomochronous patients with gastric cancer.. The proportion of male patients ware mostthan female. Patients’ ages arranged from16to45years old, the average age was40.51years. Its clinical course is short and symptoms are not evident. There were68.75%patients whose symptom was upper abdominal pain.The prognosis of cancer patientsare usually very poor.The tumors were mainly located in pyloric part, There were45.67%patients whose diameter was＞5cm. There were34.30%patients wereBorrmann III.60.10%patierts whose tumour penetrates serosa.There were56.25%patients who has lymph node metastasis.7.21%patients whose tumour infiltratesdistant organs.There were48.56%patiernts who was radical operated.The study indicated that the gender, family history, CEA levels, TNM stage,local invasion, lymph node metastasis, distant metastasis, tumor location, tumor size,tumor differentiation, without taking radical surgery, postoperative adjuvantchemotherapy, and whether a new palliative way effect young patients with gastriccancer prognostic factors.Conclusions：1.Young gastric cancer patients were observed more frequently inmale and ages ranged from36to45years old. The symptoms of gastric cancer inyoung patients wasn’t typical and clinical stages are usually very poor when diagnosed.The tumors were mainly located in pyloric part.2.The study showed that TNM stage,depth of invasion, lymph node metastasis, distant metastasis, tumor location, tumorsize, degree of tumor differentiation, without taking radical surgery is an independentprognostic factors, and radical operation was a protective factor for prognosis. Early correct diagnosis and individualized treatment is important for young patients withgastric cancer survival prognosis.