A Study Of Assessment And Application Of SWI And SWIM In Normal Deep Brain Veins And Traumatic Brain Veins Injuries

Research purposes This study has the following purposes:1. To evaluate the ability of susceptibility weighted imaging (SWI) and susceptibility weighted imaging mapping (SWIM)of3-telsa magnetic resonance to display the intracranial deep venous system;2. To investigate the application value of SWI and SWIM in traumatic brain veins injuries.Research method120subjects who had intracranial venous system diseases and had had MRI examination in the Second Xiangya Hospital of Central South University were included in this study. Fifty-six were males, sixty-four are females. The ages of the subjects range from13-55, with an average age of35.04. Clinical and conventional MRI scan shows that none of the subjects had intracranial space-occupying lesion, vascular malformation, sinus thrombosis or other related diseases. Two senior image practitioners analyzed the statistics about the display of the deep venous system and reached a consensus.Collect60cases of traumatic brain injuries in the Second Xiangya Hospital of Central South University from November,2012to December,2013. Among the60subjects,37are males,23are females. The ages of the subjects range from13to55, with an average age of39.05. All the subjects received two times of magnetic resonance examination respectively within72hours and after they got injured for one month and renamed them respectively acute group land reexamine group2. Clinical and conventional MRI shows that none of the subjects had intracranial space-occupying lesion, vascular malformation, sinus thrombosis or other related diseases. Two senior radiologists judged and counted the number of hemorrhagic foci displayed by different sequences, and excluded the questionable hemorrhagic foci. With the aid of phase diagram of continuous levels, they radiologists ruled out small vessel section, intracerebral foreign body, air and skull-related artifacts. The high signals on the SWI phase and SWIM meant intracranial hemorrhage foci. The radiologists also recorded the numbers of hemorrhagic foci detected respectively by conventional MRI sequences and by SWI sequences, the distribution of the the hemorrhagic foci, and the corresponding relationship between hemorrhagic foci and damaged blood vessels.Research Results This study discovered that SWI and SWIM could display very clearly the morphology and the anatomical sturcture of intracranial deep veins. The2-point display ratio of large and medium deep veins is100%, and the2-point display ratio of small deep veins is over83.3%. The2-point display ratio of vena septi pellucidi and venous thalamis stratum also reached100%. In acute group1, SWI and SWIM detected1,105hemorrhagic foci, T1WI sequence dectected741, T2WI sequence detected722and FLAIR sequence detect779. Therefore, SWI and SWIM can detect more hemorrhagic foci than conventional MRI sequences (P＜0.05); and conventional MRI sequences T1WI、T2WI and FLAIR shows no significant difference in the their ability to display hemorrhagic foci (P＜0.05). In reexamine group2, SWI and SWIM detected1,001hemorrhagic foci, T1WI sequence dectected636, T2WI sequence detected652and FLAIR sequence detect723. Therefore, SWI sequence can detect more hemorrhagic foci than conventional MRI sequences (P＜0.05); and conventional MRI sequences T1WI、T2WI and FLAIR shows no significant difference in the their ability to display hemorrhagic foci (P<0.05)o Further more, In acute group1, SWI and SWIM detected57damaged brain veins, Characterized by vascular enlargement, edge coarse, signal obviously uneven and so on; among the1105hemorrhagic foci detected by SWI and SWIM,277hemorrhagic foci can found their damaged brain veins。Conclusions SWI and SWIM can display the intracranial deep venous system fairly well, including its morphology and anatomical structure. In traumatic brain injury cases, SWI sequence can display the degree of change and damage of the cerebral vascular morphology. Compared with conventional T1WI and T2WI sequences, SWI can detect more minor brain hemorrhagic foci and show the corresponding relationship between hemorrhagic foci and damaged blood vessels. Therefore, SWI and SWIM can play an irreplaceable role in the accurate diagnosis in the early stage and prognosis of traumatic brain injuries.