A Liver Pathology Analysis With Surgical Treatment For Biliary Calculus Or Inflammation:57Cases Reported

Objective:To discusses in the cause and effect relationship between biliary calculus or inflammation and liver damage in the patients with surgery for benign biliary system diseases. Methods:Analyze on1479patients retrospectively who with surgery for calculus of bile duct, cholangitis, gallstone or cholecystitis from June1st2012to May31th2013,120patients’liver tissue were obtained during operation to exam the liver pathology,whose live morphology were found to be not normal by the preoperative clinical data (ultrasound, CT or MRI) or the observation during the operation. There are57cases of liver damage with unknown reason after excluding hepatitis B virus, hepatitis C virus, alcoholic liver disease, drug-induced liver disease, autoimmune liver disease, liver hydatid, hepatic cyst, hepatic hemangioma, hepatoma and biliary tract cancer. We analyzed and discussed the possibility pathogenesis of57cases. Results:(1) In this study, most of the patients with biliary tract surgery had pathological liver damage (71.93%). And liver fibrosis is50.88%.(2) In comparison with calculus of bile duct and cholangitis, gallstone and cholecystitis is more easy to merge steatosis (47.1%vs17.5%, P<0.05).(3) Steatosis is more easy to merger inflammatory necrosis (26.7%vs7.1%, P<0.05).(4) Diabetes easily merge inflammatory necrosis (42.9%vs8.0%, P<0.05). Conclusion:In these patients with surgical resection for biliary tract disease of this study, quite a number of their clinical symptoms may be the performance of non-alcoholic fatty liver disease. Therefore, it’s necessary to strengthen the assessment of metabolic liver disease patients, especially the ones with non-alcoholic fatty liver disease, before deciding whether to solve biliary calculus or inflammation by surgical methods.