The Analysis Of Association Between Metabolic Syndrome Or Its Severity And Heart Rate Variability Or Borareflex Sensitivity In Chinese Population

PurposeA large number of basic and clinical studies suggested the relationship between metabolic syndrome that insulin resistance as the central link and cardiovascular disease.Studies have found that the disease morbidity and mortality of metabolic syndrome in patients with cardiovascular were higher than non-metabolic syndrome.The heart rate variability (Heart rate variability HRV) analysis is a noninvasive method of quantitative evaluation of cardiac autonomic function. Prospective study found the relationship between HRV and cardiovascular disease risk, the HRV lower, the greater the risk of cardiovascular events. It was found that the pation with reduced HRV had the higher incidence of myocardial infarction than those with normal HRV in the follow-up significantly.Baroreflex sensitivity (Baroreflex sensitivity, BRS) is an effective method to cardiac autonomic nerve function status, that can be used as a cardiovascular disease risk stratification. It was great significanct in detecting the sudden death in the pation with myocardial infarction by BRS. The mortality in reduced BRS patients with myocardial infarction increased significantly, BRS of the mortality of patients with heart failure group was significantly lower than the survival group in the follow-up study.The purpose of this study was to evaluate the association between the metabolic syndrome and cardiac autonomic function. Methods1. The study objects were selected in Baoshan Community with2119individual,35years old-75years old, excluded potential confounding factors, collect general information, physical examination, biochemical parameters, short-range frequency domain HRV and BRS detection.2. Metabolic syndrome clinical diagnostic criteria based on NCEP (ATP III) in2001. divided into six groups.3. SPSS13.0software was used for normal distribution test of each variable, in line with normal or near-normal distribution variables "mean±standard deviation; variables with skewed distribution of the median (25th percentile-75th percentile)"to indicate, analyzing the correlation between metabolic syndrome component with the skewed variables afterting Log10conversion. ResultsThree HRV components of total (1gTP), low frequency (1gLF) and high frequency (1gHF) power and BRS components were different among groups according to MetS severity score (P<0.05for all).ConclusionOur find that MetS and IR were significantly negatively associated with CAF independently. Two MetS components of FPG and BP were negatively correlated with CAF. There is a tendency toward decreased HRV or BRS components with increasing MetS severity score.