| Objective:The treatise of xiao xian xiong decoction is too brief in the book Shanghan lun, as a famous decoction of Zhang zhong jing,it has experienced thousands oftimes of clinical application and research. In order to uncover the law of theapplication of this decoction, It is necessary to organize and summarize the thosetheories of this decoction and syndromes of Xiao Jie Xiong essentially,which providesa basis for clinical application.Methods:On the basis of collecting data extensively, all the datas were classified intoseveral parts according to different types: data of prescriptions and comments on xiaoxian xiong decoctionã€data of clinical application and that of pharmacologicalexperiments, hoping to organize and summarize the decoction and syndromes of XiaoJie Xiong by using the method of context interpretation and frequency data statistics,1)The original text was analysed sentence by sentence and we explored somequestions such as the diseased region "under the heart"ã€feeling pain after beingtouched ect. We also distinguished the difference among Jie Xiongã€visceral bind andstuffiness,by comparing the different data of prescriptions and comments on xiaoxian xiong decoction from different ancient doctors,we hope to summarize thosecharacteristics of xiao xian xiong decoction;2)We hope to know about the diseasespectrumã€syndromesã€drug dosage and the clinical change of different herbalmedicines by analysing the data of clinical application;3) The data ofpharmacological experiments can provide functional evidence of xiao xian xiongdecoction;4)we summarized the clinical experience of our tutor corresponding to theclinical researchs.Results:1. The basis pathogenesis of xiao xian xiong decoction: Intermingled phlegmand heat underneath the heart;2. The effect of xiao xian xiong decoction: clearingheatã€eliminating phlegm and eliminating stagnation;3. The disease spectrum: xiaoxian xiong decoction can not only be used for the disease of xiao jie xiong which havelots of clinical syndromes but also others illnesses;4.Main symptoms: Chest tightnessã€Bloatingã€stomachacheã€coughã€nausea and vomitingã€chest painã€Painin ribs ect, we can use those secondary symptoms as a reference like bitter tasteã€drymouth(unwilling to drink)ã€fatigueã€insomniaã€acid reflux ectï¼›5. Xiao xian xiongdecoction has been mainly applied to the digestive system,such as chronic gastritisã€chronic and acute cholecystitis〠reflux esophagitis ect; those diseases ofcardiovascular system such as coronary heart diseaseã€angina pectoris ectï¼›thosediseases of respiratory system such as chronic and acute bronchitisã€bronchial asthmaectï¼›and others diseases caused by Intermingled phlegm and heat which belong toothers systemsï¼›6. The tongue coating and pulse condition: red tongueã€greasy furã€yellow furã€Stringy pulseã€slippery pulse or rapid pulse;7. General condition:â‘ Gender: The male to female ratio is1.46:1,that is, the majority of the patients aremen,â‘¡Those people whose age is among41-50or51-60are more easy to get theillness of "xiao jie xiong",the proportion of the two groups accounts for59.59percentï¼›8. Based on the different symptoms of patients,the basic prescription of xiaoxian xiong decoction is often be added with herbal medicine for regulating QI flowã€tonifying herbal medicine(especially herbs for tonifying Qi)ã€herbal medicine forinvigorating blood circulation and eliminating stasisã€herbal medicine for resolvingphlegm and relieving cough or relieving asthmaã€heat-clearing herbal medicine anddamp dispersing herbs ect, specifically speaking,the most commonly used herbalmedicine are fructus aurantii immaturusã€fructus aurantiiã€curcumaeã€Radix Bupleuriã€rheum officinaleã€salvia miltiorrhizaã€Bamboo Shavingsã€official Magnoliaã€Poriacocosã€Cape jasmineã€Scutellaria baicalensisã€almond Almondã€Tangerine Peel ect.Conclusion:The basis pathogenesis of xiao xian xiong decoction is intermingledphlegm and heat underneath the heart because of the invasion of the exteriorpathogenic factors into the interiorã€therapeutic errors for curing disease caused byexogenous pathogenic factor and heat invagination. The xiao xian xiong decoctioncan also be used when the pathological situation "intermingled phlegm and heatunderneath the heart" was resulted by other causes, clearing heatã€eliminating phlegmand eliminating stagnation are basic effects of xiao xian xiong decoction, the xiaoxian xiong decoction can be applied to different systematic diseases if we have a deep knowledge of the basis pathogenesis and basic effect of this decoction. |