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Analysis Of Ningxia Area Risk Factors For Early Recurrence Of Primary Hepatocellular Carcinoma After Radical Hepatectomy

Posted on:2015-02-23Degree:MasterType:Thesis
Country:ChinaCandidate:H Q YuanFull Text:PDF
GTID:2284330452493927Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective To explore the risk factors for early recurrence of primary hepatocellularcarcinoma after radical hepatectomy.Methods Methods Retrospective analysis, Data and follow-up results of98cases ofprimary liver cancer clinical pathology resident population collected from Ningxia generalhospital attached to Ningxia Medical University during2001-2012. By Cox proportionalhazards regression model, Select gender, ages ago, hepatitis B surface antigen, preoperativeALT, preoperative alpha-fetoprotein, preoperative liver function Child classification, tumorsize tumor, the satellite nodules, vascular invasion, hilar clamping time, tumor capsule, liversclerosis, tumor grade13indicators to analyze the impact of early relapse.Results98cases ofradical resection of liver cancer cases,38cases of early recurrence,the recurrence rate was38.8%, by Cox proportional hazards regression model Univariateanalysis showed that age, tumor size, preoperative liver function Child classification, tumordifferentiation, vascular invasion, liver sclerosis, tumor grade is a risk factor for earlypostoperative recurrence..Conclusion:Patients with primary liver cancer after radical resection of liver cancer has beenaffected by the high rate of relapse of postoperative long-dated curative effect. Ningxia areaof primary liver cancer patients underwent radical resection, recurrence (early recurrencewithin1years) risk factors: age, tumor size, preoperative Child classification of liver functionclinical staging, tumor, liver cirrhosis, with vascular invasion. According to the clinical containing these patients with high risk factors, we should strengthen the follow-up afteroperation, so as early detection of tumor recurrence and metastasis potential, earlyintervention and individualized treatment to improve the prognosis of the patients.
Keywords/Search Tags:Primary liver cancer, Hepatectomy, Cox proportional hazard model, Prognosis
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