The Value Of MRI In Detectiong Bone And Seminal Vesicle Metastasis Of Prostate Cancer

Objective: With bone metastasis or not is important for the clinical staging of prostatecancer. Now the examinations in staging include MRI, bone scingraphy, CT and PET/CT.To study the value of MRI in the diagnosis of bone metastasis of prostate cancer,and tocompare MRI and Bone Scintigraphy in detecting bone metastasis of prostatecancer,Choosing the best one to make a accurately staging is helpful to select areasonable treatment and have a better prognosis.Methods and Materials: A retrospective study of252cases of pathology provedprostate cancer, who scaned with conventional MRI, MRI enhancement andDWI.Analyzing the imaging of pelvic,To obtain and compare the the sensitivity.specifilityand accuracy of MRI and Bone Scintigraphy in detecting bone metastasis of prostatecancer.Results: The PSA of80%patients with bone metastasis of prostate cancer is above50ng/ml,wihle92%patients without bone metastasis,thePSA<50ng/ml.thesensitivity.specifility.accuracy.PPV and NPV of MRI in detecting bone metastasis ofprostate cancer is respectively99.2%,100%,99.2%.100%.99%while Bone Scintigraphy85.1%,84.3%,84.5%.60%.95.4%。Conclusion:1. MRI has a higher specificity and PPV, which has an advantage over bone scintigraphyin showing lesions in pelvic cavity.2. Bone scintigraphy has a wider vision and can estimate the bone metastasis of thewhole body.3. MRI and bone scintigraphy can complement each other and is beneficial for clinicalstaging of prostate cancer accurately.4. MRI coronal and sagital sequences is essential and can effectively improve thedetection rate of lesions Objective: To find the value of MRI in diagnosing seminal vesicle invision of prostatecancer,with traditional MRI and functional MRI.To analysis the value of ADC differencesfor the differential diagnosis of seminal invision and to compare the value of traditionalMRI.MRI enhancement and DWI in detecting seminal invision of prostate cancer.Methods and Materials: A retrospective study of252cases (504seminal vesicle glands)of pathology proved prostate cancer, who scaned with conventional MRI, MRIenhancement, and DWI.Measure the ADC values of the prostate cancer and both seminalvesicles, then do the dependent-samples t test.While obtaining the sensitivity, specificityand accuracy of conventional MRI, enhanced MRI, DWI and their combination indiagnostic of seminal vesicle invasion.Results: The ADC values of SVI.the Prostate cancer with seminal vesicle invision. theenhanced but no seminal vesicle gland invision and the Prostate cancer without seminalvesicle invison is respectively (0.98±0.02)x10-3mm2/s,(0.81±0.14)x10-3mm2/s，(1.59±0.04)x10-3mm2/s，(1.01±0.12)x10-3mm2/s. The ADC value of SVI is also lowerthan the enhanced but no seminal vesicle gland invision.(P<0.05),The ADC values of theProstate cancer with seminal vesicle invision is markedly lower than the ADC values ofthe Prostate cancer without seminal vesicle invision.(P<0.05). The ADC values of theProstate cancer with seminal vesicle invision is lower than the ADC of SVI.TheSpecificity of conventional MRI, enhanced MRI, DWI and their joint in the diagnosis ofseminal vesicle invision of prostate cancer are93.1,97%,99.5%,99.7%. Sensitivity of100%,100%,100%and94%. Accuracy of93.6%、98%、99.4%,99.8%。PPV of54%，78.7%，97.2%，97.3%，NPV of100%，100%，99.5%，100%。 Conclusion:1. The ADC difference of seminal vesicle is valuable in judging seminal vesicles invisionor not in patients of prostate cancer.2. The combination of multi-sequences of MRI is helpful in diagnosing seminal vesicleinvision accurately.