The Relationship Of The 156 Cases Patients Between The Hispathology Diagnosis And The Imaging Features Of The Solitary Pulmonary Nodules

Objective To investigate the relationship between histopathology diagnosis and imaging features of solitary pulmonary nodules(SPN).Methods The dates of 156 cases with solitary pulmonary nodules that were confirmed by hispathology in The First Affiliated Hospital of Guangxi Medical University hospital from June 2012 to September 2014.Of these 156 patients, 81 cases (51.92%)were male and 75 cases (48.08%) were female.The average age of the 156 cases patients was 56.96±11.00 years. The patients were packed By histopathologic findings into malignant group and benign lesions. The relationship was analyzed between the groups and the the imaging features.Results A total of 156 patients that showed solitary pulmonary nudoles were enrolled in this study. The histopathology results show ed that 148 cases of the total were malignant lesions (94.87%),which included adenocarcinoma 124 (79.48%), squamous cell carcinoma in 12 patients (7.69%), and the remaining large cell carcinoma, lung cancer and other types of neuroendocrine tumors were 5 cases (3.21%),5 cases (3.21%),2 cases (1.28%); benign lesions were 8 cases (5.13%), which included two cases of tuberculosis,2 cases of inflammation, inflammatory pseudotumor, inflammatory granuloma, cystic lesions, leiomyoma was 1 case respectively.Of 156 cases patients,lung lesions located at right lobe, left lobe, upper lobe, middle lobe and lower lobe were 91 cases (58.33%),65 cases (41.67%),81 cases (51.92%),11 cases (7.05%) and 64cases (40.03%) respectively.6 cases of SPN sized≤10 mm(3.85%),88 cases of SPN sized 10mm-20mm (39.74%) and 62 cases of SPN sized 20mm-30mm(39.74%); Besides, patients with lobulation, spiculation, pleural indentation, vacuole sign and vascular convergence sign were 93cases (59.61%),88cases (56.41%),43cases(27.56%),29cases(18.59%). the diagnosis of malignant lesions that with lobulation, spiculation, pleural indentation, vacuole sign and vascular convergence sign were 97.85%,96.59%,95.12%, 93.10%. The average density lesion of the solitary pulmonary nodules were 1-60Hu in the majority, which showed 74.36% (116/156).The probability malignant lesions was 95.69%(111/116).The focal ground-glass opacity accounted for 12.18% (19/156), but the probability malignant lesions were 100%(19/19); The patients of the solitary pulmonary nodules that were≥40 years accounted for 94.23% of the lesions (147/156).Conclusion 1.solitary pulmonary nodules were more common in the people that the age were over 40 years;2.solitary pulmonary nodules were common desiged adenocarcinoma, squamous cell carcinoma, large cell carcinoma, other more common types of lung cancer respectively;3.the malignant solitary pulmonary nodules would have lobulation, spiculation, pleural indentation, vacuole sign or vascular convergence sign, the positive was 97.85%,96.59%, 95.12%,93.10% Respectively;4.Most of the lung focal ground-glass nodules were malignant lesions;5.the pathological diagnosis of solitary pulmonary nodule have no relationship with their distribution.