The Clinical Indicators Of The Impact Of Taohongsiwutang For Limb Fractures Postoperative Inflammation

ObjectiveThis clinical problem by comparing the experimental and control groups before and after treatment serum leukocyte, neutrophils, CRP, IL-6, TNF-a levels, evaluate Taohongsiwutang limb fracture in reducing postoperative inflammation Value and clinical efficacy.MethodsBy prospective study, according to the set of inclusion criteria, exclusion criteria of the study subjects were randomly divided into an experimental group and a control group,30 patients in the control group:Ai Coke 2g+0.9% NaCl 100ml q8h ivd, plus compound sodium chloride 500ml or 5% glucose 500ml ivd qd; experimental group:Ai Coke 2g+0.9% NaCl 100ml q8h ivd, plus compound sodium chloride or 5% glucose 500ml 500ml ivd qd, plus oral medicine Taohongsiwutang treatment. Where Ai cola infusion two days, Taohongsiwutang oral seven days. The control group and the experimental group were preoperatively (day of surgery), postoperative day 1,7 days morning 7:00 fasting blood, venous blood 2ml, heparin and mix immediately inspected; blood, CRP detected by Guangdong Provincial Hospital of laboratory detection; IL-6, TNF-a detected, respectively, in fasting blood 3-5ml,1500r/min centrifugal 10min after the serum and stored at-20 ℃ refrigerator spare, after aggregated into Elisa reagent batches box testing. The two groups were compared blood (white blood cells, neutrophils), CRP, IL-6, TNF-a level changes. Application SPSS19.0 statistical software for data collected for statistical analysis, measurement data "x±s" between the two groups were compared using two independent samples t-test, paired t-test was used to compare the group,count data using χ2 test data data for statistical analysis, P<0.05 was considered statistically significant.ResultsBasic information:experimental group and control group sex structure and composition, age composition and operation time, statistical analysis, the P>0.05, described the two groups of gender, age, composition and operation time was no difference, comparable.Results of clinical trials:the preoperative (day of surgery), the first day after the experimental group and the control group of white blood cells, neutrophils, C-reactive protein, tumor necrosis factor and interleukin-6 values were statistically independent samples t test, obtain P>0.05, no significant differences between the two groups described, comparable; for seven days after the first experimental group and a control group of white blood cells, neutrophils, C-reactive protein, tumor necrosis factor and interleukin-6 values were statistically independent sample t test, draw white blood cells, neutrophils, P value of C-reactive protein P> 0.05, the difference was not statistically significant; the seventh day after the experimental group and the control group tumor necrosis factor, interleukin-6 P value of P<0.05, the difference was statistically significant, indicating Taohongsi-wutang decoction can reduce limb fracture surgery in serum tumor necrosis factor and interleukin-6 content.ConclusionThe research results show that Taohongsiwutang not be able to reduce serum limb fracture surgery leukocytes, neutrophils, CRP levels, can reduce IL-6, TNF-a levels in serum, the description taken with limb fracture surgery Taohongsiwutang can reduce postoperative inflammation.