Effect Of Short-term Liraglutide Therapy And Intensive Insulin Therapy On B-cell Function In Type 2 Diabetes Mellitus

ObjectiveBy detecting the c-Peptide level of new diagnosed type 2 diabetes mellitus before and after diffferent therapy,we want to found the difference of the effect of the two different therapy on the B-cell function. MethodNew diagnosed type 2 diabetes mellitus Patients in hospital from 2012.3 to 2013.6 were randomly divided into Liraglutide group and intensive insulin group. C-Peptide were detected before and after 20 days therapy with Liraglutide or intensive sunsulin and the Statistic analysis for the data were Performed. ResultsAfter 20 days therapy, the reduce speed to the target value of blood glucose level in the inrensive insulin group was faster satistically than that in the Liraglutide group. However, the data of c-Peptide level show that the B-cell function of Patients in the Liraglutide group were better recovered than that in the intensive insulin group. ConclusionEven in the short-term therapy, Liraglutide therapy is superior to the intensive insulin therapy in recovering the B-cell function and is Propitous to long-term glucose control whiche Provide better security.