| Objective: Colon Slow both transmissive Constipation(missile Transit Constipation) is the common disease, frequently-occurring disease anus bowel division, the serious influence to promote the quality of life of patients, greatly endanger the patient’s physical and mental health, can cause nausea, vomiting, loss of appetite, digestive system disease, can even induce angina pectoris, myocardial infarction and cerebrovascular disease. Slow both transmissive constipation for stool frequency decreases, the major clinical manifestations of no meaning, no poop when the anus dre, the anorectal pressure is normal, without the anus belly unwell, tenesmus and other symptoms. On STC is the main reason caused colon transmission is slow, belong to primary, functional, tardy constipation. Due to its etiology is unclear, and symptoms stubborn illness repeatedly, result in treatment effect is not ideal, than with pain.At present there is no effects of drugs and clinical treatment, so for constipation, especially slow both transmissive constipation, increasingly brought to the attention of the medical community. In this paper by differentiation of kidney and on the basis of the relationship between constipation, using the holistic concept and treatment based on syndrome differentiation in TCM thinking method, from the perspective of nourishing kidney Yin, since the quasi zi yin yun chang tang, and added new treatment way for clinical treatment on STC.Methods: Clinical choice of Hebei traditional Chinese anorectal outpatient and hospitalized patients, a total of 60 cases, 38 cases of women, male, 22 cases with on STC and kidney Yin deficiency type constipation diagnosis of TCM into standard, patients signed the informed consent and voluntary medication. Patients were randomly divided into three groups, group A and group B, group C 20 cases in each group. Group A(ziyin kidney and intestine soup combined cisapride, cisapride will choose 5 mg, xi ’an yeung sum, H1096028920 approved by the state, the same below) and group B(A laxative capsule combined cisapride, laxative capsule selects Beijing tongrentang technology development co., LTD., pharmaceutical factory, Z11020326) approved by the state, group C(cisapride), the statistical analysis of three groups of patients with gender, age, degree of illness weight difference has no statistical significance(P>0.05), comparable. Treatment for 1 week for a period of treatment, a total of four courses, after the end of January after treatment the curative effect and other follow-up. Comparing three groups total effective rate, symptoms before and after the treatment of improvement and safety indicators, such as to make evaluation. All the research data using SPSS13.0 statistical software, statistical processing, average metering data to add and subtract the standard deviation(’x and s), in accordance with normal distribution using analysis of variance, does not conform to the normal distribution of the rank and inspection are classified. P<0.05 for statistically meaningful.Results:1 Drop in three groups of symptom score after treatment, clinical symptoms and some improvement, three groups of patients and treatment before have obvious difference.(P<0.01)2(1) A group cure rate 41.75%, show the efficiency of 22.88%, effective rate was 15.63%, no efficiency by 19.74%, total effective rate was 80.26%;(2) the B group cure rate 26.67%, show the efficiency of 24.66%, effective rate was 20.00%, no efficiency by 28.67%, total effective rate was 71.33%.(3) C group cure rate 16.70%, show the efficiency of 29.46%, effective rate was 10.00%, no efficiency by 43.84%, total effective rate was 56.16%.Three groups of the total effective rate of the statistical analysis, there are significant differences(P<0.05).3 three groups after 1 month of drug withdrawal compared with significant difference(P<0.01), group A is better than that of group B is better than that of group C.4 three groups in terms of improving disease concurrently, and group A is better than that of group B and group C.5 security index of three groups of patients during treatment were not found obvious adverse reactionsConclusion: Can nourish the kidney and soup combined cisapride will force can promote colonic peristalsis, promoting defecation, can significantly improve the slow both transmissive patients with constipation defecate time is long, difficult defecation, dung qualitative hard, defecation time interval is long wait for a symptom, have remedial effect to slow both transmissive constipation, and the effect is better in terms of improving disease concurrently; The scheme has the characteristics of simple, economic and effective, and good clinical safety, found no obvious adverse reactions and side effects. Of kidney Yin deficiency type slow both transmissive constipation has good treatment effect, can fundamentally have the effect of treatment. |
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