Long-term Follow-up In Stenting To Prevent Recurrent Intracranial Artery Stenosis Stroke And The Risk Factor Analysis

Objective Stroke is the firstly disease of mortality and morbidity, and the most common cause is symptomatic intracranial atherosclerosis artery stenosis. Traditional medicine therapy and stenting based on medicine are both could improve the outcome level of stroke patients. Whlie stenting for the effect of long-term secondary prevent in intracranial ischemic stroke has no clear conclusions.The safety and effictiveness of intracranial stenting also has in the research stage. Because of the exsist of risk factor, at the same time, intracranial atherosclerosis artery ischemic stroke has a higher recurrence rate althought in activity medicine therapy and invascular intervention. This article has discussed the mid-long term effect witch invascular stenting to secondary prevention by retrospective study the 191 syptomatic intracranial atherosclerosis artery ischemic stroke in general hospital of military in Lanzhou.At the same time to disscuss the risk factor of recurrence.Methods A toal of 191 cases treated for ischemic storke of intracranial stenosis from June 2008 to October 2013 in our hospital were reviewed.The clinical character such as hypertension,diabetes mellitus,smoke,obedience of drug,and so on,and out comes such as ischemic stroke,myocardial infarction and death from any cause,were recorded,and compared stenting group with drug goup, and analysed in Logistic regression analysis with the risk factor.Results 191 cases (162 in drug group,29 in stent group)were follow-uped with 12-76 month(32.8 mean month).The incidence rate of ischemic stroke on two groups in 1 year was 8.0%:6.9%,2 year was 16.9%:12.0%,3 year was 17.6%:14.3%, over 3 year was 19.0%:16.7%.There was no significant difference in two groups in incidence rate. The Logistic analysis shows that Age (OR=1.675,95%CI:1.296-2.142, P＜0.05),Hypertension (OR=3.379,95%CI:2.472-4.924, P＜0.05), Diabets mellitus(OR=1.473,95%CI:1.228-2.301, P＜0.05),Obidience of lipid-dicresing drug (OR=2.533,95%CI:1.661-3.732,P<0.05)are correlation with recurrent of ischemic stroke. sex (OR=2.599,95%CI:0.462-14.608, P>0.05、obidience of antiplatelet drugs(OR=1.421,95%CI:1.114-1.813, P>0.05)、smoke(OR=1.6020,95%CI:942-2.724) are incorrelation with recurrent of ischemic stroke.Conclusions For patients of symptomatic intracranial stenosis,the effective of prevent recurrent stroke is equality. Age, hypertension, diabets mellitus and obidience of lipid-dicresing drug is correlation with recurrent of ischemic stroke.When to disscuss,control of the other risk factor may reduce the recurrence rate of stroke,and the diversificate assess of stenting patient will be more important meaning to improve the result of stenting therapy.