| Objective:To investigate the presence of gender differences in clinical characteristics in patients presenting with first acute ST-segment elevation myocardial infarction (STEMI), treated with primary percutaneous coronary intervention (PCI).Methods:A total of 211 patients (16.59% women) presenting with STEMI who underwent primary PCI within 12 hours following onset of ischemic symptoms were selected. Those patients were divided into male group (n=176) and female group(n=35). Clinical data, angiography findings, PCI procure data and echocardiographic evaluation were compared between genders.Results:Compared with male group, female had older mean age(67.00±8.45 vs 60.34±11.12years,P=0.001), more co-morbidities and longer symptom duration(428.29±228 vs 330.68±232min,P=0.024), whereas, the rate of smoking habit was significantly lower in female than that in male group(P<0.001). Female had higher mean platelet volume, total cholesterol, LDL-C than male, whereas, male had higher creatinine and hemoglobin than female.There were no difference in hospital care, length of hospital stay and in-hospital mortality between each group. A logistic multivariate analysis model revealed that female(OR=2.50 95% CI 1.06-5.89 P=0.036),anterior myocardial infarction(OR=6.35 95% CI:3.44-11.71 P<0.001) were positively associated with left ventricular ejection fractions<50%.Conclusions:Female following first STEMI are older, more co-morbidities and longer symptom duration. Despite receiving similar treatment as male patients, female patients demonstrate a worse systolic left ventricular function. |
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