Nao Luo Xin Tong Ke Li In Treatment Of Ischemic Stroke(cerebral Infarction) During The Acute Period Of Syndrome Of Stagnation Of Qi Deficiency And Blood Stasis Syndrome Study Of Clinic

Objective:to evaluate clinical effect of Xin’an medical experience Nao Luo Xin Tong Ke Li characterised by benefiting Qi and activating blood circulation resuscitation on ischemic stroke therapy(Cerebral infarction) acute period of qi deficiency and blood stasis syndrome,observe the role played after neurological deficits and daily life changes and oxidative stress in ischemic stroke acute of qi deficiency and blood stasis syndrome, According to the related physical and biochemical index change characteristic,discuss the possible mechanism of Nao Luo Xin Tong Ke Li on ischemic stroke(cerebral infarction) during the acute period of qi deficiency and blood stasis syndromeMethods:90 patients were consistent with the diagnostic criteria of ischemic stroke therapy(Cerebral infarction) acute period of qi deficiency and blood stasis syndrome, who were randomly divided into three groups including Nao Luo Xin Tong group、Tong Xin Luo group and control group,the control group was given conventional symptomatic treatment,Tong Xin Luo group on the basis of routine treatment given Tong Xin Luo capsule,Nao Luo Xin Tong group on the basis of conventional therapy plus Nao Luo Xin Tong Ke Li.To observe index values change on the day of admission,7 days and 14 days of treatment, treatment of Wednesday 4 different time sites on neural function defect score,activities of daily living score,a modified Rankin scale, TCM syndrome integral,hemorheology,blood coagulation function, soluble intercellular adhesion molecule 1,tumor necrosis factor alpha,vascular endothelial growth factor to evaluate clinical effect of control group、Tong Xin Luo group and Nao Luo Xin Tong group.Results:Nao Luo Xin Tong Ke Li in treatment of ischemic stroke(cerebral infarction) with Qi deficiency and blood stasis therapy on day 14 of the total efficiency of 90%, better than the Tongxinluo group and control group,statistically significant differences(P < 0.05), significantly improve the patients’ clinical symptoms and signs.Nao LuoXin Tong KeLi in treatment of ischemic stroke(cerebral infarction) during the acute period of qi deficiency and blood stasis syndrome may improve patient degree of neural function defect,treatment for 7 days,14 days were superior to the control group and the Tong Xin Luo group,statistically significant differences(P < 0.05 or P < 0.01), can significantly improve the patient’s symptoms and signs,improve daily activities of daily living score and reduce the improved m RS classification,to reveal the important position of qi and activating blood circulation in the treatment of ischemic apoplexy in restoration stage of qi deficiency and blood stasis syndrome,Nao Luo Xin Tong Ke Li on ischemic stroke acute of qi deficiency and blood stasis of patients have a good effect.Symptom scores before and after treatment,Nao Luo Xin Tong Ke Li in the treatment group is lower than control group and Tong Xin Luo group decreased significantly,and were significant(P < 0.05 or P < 0.01).Clinical physicochemical indexes:Nao Luo Xin Tong group coagulation series,blood rheology indexes related to numerical changes than the control group and the Tong Xin Luo group were obviously improved(P < 0.05), Description of coagulation mechanism in the acute phase of cerebral infarction is still needed to monitor,Nao Luo Xin Tong can obviously improve the ischemic apoplexy convalescent patients with Qi deficiency and blood stasis of fibrinolysis and coagulation function. VAP – 1,The control group,Tong Xin Luo group and Nao Luo Xin Tong group three to group VAP – 1 decreased,despite changes in control group,but no statistical significance,compared with the control group,Tong Xin Luo group and Nao Luo Xin Tong group,VAP – 1significantly improved(P < 0.05 or P < 0.01),Nao Luo Xin Tong group was significantly better than the Tong Xin Luo group(P < 0.05), description of inflammatory mediators in ischemic apoplexy convalescent patients with Qi deficiency and blood stasis in the body play an equally important role,by decreasing the content of inflammatory mediators,can obviously reduce the ischemic stroke acute of qi deficiency and blood stasis symptoms and signs. SOD、MDA:the control group,Tong Xin Luo group and Nao Luo Xin Tong group three to group, has decreased,despitechanges in control group, but no statistical significance,SOD、MDA compared with the control group,Tong Xin Luo group and Nao Luo Xin Tong group o LAB,VAP-1,CRP better has obvious improved(P < 0.05 or P < 0.01),Nao Luo Xin Tong group was significantly better than the Tong Xin Luo group(P < 0.05),detection of vascular conditioning and growth factors in ischemic stroke acute of deficiency of Qi and blood stasis in the role,that of Nao Luo Xin Tong through effects on vascular and tempered and growth factor loss and improvement of ischemic stroke racute of Qi and blood stasis in patients with clinical symptoms.Safely index : Blood routine 、 urine routine 、 stool routine 、 kidney 、 liver and electrocardiogram on three groups between pre treatment and post treatment are normal and adverse drug reaction did’t occur during the treatment.1、Ischemic stroke acute period is the main pathogenesis of deficiency of Qi and blood stasis, the disease is located in the brain,Qi-oriented blood stasis as a standard.Xin’an s experience of Naoluoxintong particles is administer thoroughly,or both,has good theoret-1ical basis,can reverse mechanism; 2、Mechanisms of ischemic stroke acute of qi deficiency and blood stasis syndrome pathological process has close related to the coagulation, inflammation,vascular mechanism of quenching and tempering and growth factors; 3、Nao Luo Xin Tong Ke Li on ischemic apoplexy convalescent patients with Qi deficiency and blood stasis has obvious curative effect and the clinical usefulness of the superior Tongxinluo capsule,thereby for ischemic stroke acute of qi deficiency and blood stasis clinical intervention provides new prescription medication. 4、Nao Luo Xin Tong Ke Li on ischemic stroke therapy(Cerebral infarction) acute period of qi deficiency and blood stasis in blood stasis pathogenesis and mechanisms of coagulation, inflammation, vascular mechanism of quenching and tempering and growth factors in multiple aspects,acting on multiple links,multiple target-1s, embodies the Chinese medicine in the treatment of cerebrovascular diseases betteradvantage.