| Object:the Metabolic Syndrome (Metabolic Syndrome, MS) is obesity, high blood pressure, high cholesterol and high blood glucose Metabolic abnormalities in many aspects of clinical Syndrome, it is not only a medical problem, is also a serious sAt present, both at home and abroad for the treatment of metabolic syndrome, and constantly develop new anti-hypertensive drugs, lipid-lowering drugs, medicines, although has certain effect to the MS, but its side effects and complications of induced that accompany, especially such as statins, Bert lipid-lowering drugs all have varying degrees of damage to liver and kidney function, make its clinical application is limited. In recent years, domestic scholars application of traditional Chinese medicine, acupuncture techniques, intervention in the treatment of MS, and give a lot of research, basic confirmed that acupuncture can enhance obesity sympathetic nerve function, inhibit the hyperfunction of parasympathetic nerve function, so as to reduce hunger, reduce appetite, weight loss; Acupuncture and moxibustion can regulate neuroendocrine function, reverse the abnormal metabolism, by observing the fasting blood sugar, triglyceride, total cholesterol, adrenaline, adrenocorticotropic hormone, cortisol in blood, saliva, thyroid, growth hormone, cortisol, adenosine monophosphate, cyclic guanosine phosphate rings, basal metabolic rate and other indicators, shows that acupuncture can strengthen the function of patients with low sympathetic adrenal system, the hypothalamus-pituitary adrenal cortex system and functions of the system of thyroid, thereby increasing energy consumption, promoting the mobilization and decomposition of fat; Acupuncture can inhibit hyperthyroidism patients with gastrointestinal digestion and absorption function, and based on some active substances in the body (cAMP,5-HT, HA, etc.), PGE2 may promote adipose decompose, the influence of the inhibition of gastric acid secretion; Acupuncture can improve the water quality of patients with salt, sugar and fat metabolism. Animal experiments found that acupuncture by choline, excited state of beta receptors and improving insulin resistance, thus realize adjust lipid metabolism, reduce the effect of body mass index. The study also suggests the acupuncture effect of tiaozhi important one way is through the regulation of neuroendocrine function.ocial problem. MS refers to human body substances such as protein, fat, carbohydrates in metabolic disorder, appear a series of syndromes in clinic, according to the metabolic syndrome. Such as sugar metabolic disorder occurs when glucose tolerance is low, cause diabetes; Fat metabolism disorder in hyperlipidemia, fatty liver, obesity, high blood viscosity, etc.; Protein metabolism disorder, appear high uric acid hematic disease (or gout), etc. And can be triggered by the above three metabolic disorders and many complications, such as high blood pressure, arteriosclerosis, coronary heart disease, stroke, etc. MS can be summarized as "eight heights":the hyperglycemia, hyperlipidemia, hypertension, high blood viscosity, high uric acid hematic disease, fatty liver, high high insulin hematic disease. Because of the complexity of the MS asked drug treatment is various, but the symptomatic treatment of western medicine is often to a single symptom, the overall treatment effect is not ideal, and therapy of TCM treatment based on overall, especially acupuncture treatment technology, can from multiple systems, multiple targets to improve the MS. Main aim of this study is to observe the acupuncture manipulation influence on MS lipid metabolism and related indicators, through clinical observation of removing the qing xie stitch regulation of lipid metabolism of metabolic syndrome.Methods:72 cases of patients with metabolic syndrome (is) in lipid metabolism disorders, were randomly divided into â… group (routine treatment) and â…¡ group (routine treatment plus acupuncture treatment), each group of 36 cases respectively, â… group using oral fenofibrate and simvastatin cholesterol-lowering therapy, â…¡ group except the drugs orally to acupuncture shenshu point back, often in the valley, such as acupuncture point treatment. Two groups, respectively, compared with before and after treatment of body mass index, systolic pressure, diastolic blood pressure, triglycerides, fasting blood indexes of high-density lipoprotein cholesterol (HDL-C).Results:1 General situation is before treatment group and control group:group and the control group the research object of age, gender and dyslipidemia, hypertension, obesity, diabetes cases, according to the alpha= 0.05 standard of hypothesis test, P> 0.05, no statistical significance, comparable. See table 1. BMI:treatment group (BMI is 36.34+/-4.64 in the control group a BMI of 35,71+5.35, according to the alpha= 0.05 standard of hypothesis test, P> 0.05, no statistical significance.2 Group compared to control group after treatment:curative effect analysis:the two groups after treatment group of 36 cases, functional recovery in 5 cases,5 cases were markedly effective, effective for 6 cases, total effective for 16 cases, the total effective rate was 44.5%, the control group of 36 cases, basic recovered in 4 cases,2 cases were markedly effective, effective for 4 cases,10 cases of total effective, the total effective rate was 27.8%, treatment group total effective rate of MS was obviously higher than that of control group, the statistical significant differences (P< 0.05). Are shown in table 2.3 Research component type effect analysis:the treatment group of 36 cases,17 cases gastric bowel relieving heat type, which healed in 2 cases,2 cases were markedly effective, effective in 2 cases,10 cases were invalid, the total effective rate was 35.3%; Phlegm turbidity type 9 cases of pixu (spleen deficient), of which the healing in 2 cases,1 case had marked effect, effective in 2 cases,4 cases were ineffective, the total effective rate was 55.6%; 10 cases of spleen and kidney Yang deficiency type, which recovered in 1 case,2 cases were markedly effective, effective in 2 cases,5 no effect, the total effective rate was 50%. Statistical analysis of wet plate type and spleen kidney Yang deficiency type pixu (spleen deficient) there was no significant statisticalsignificance, both similar effects, respectively compared with gastric bowel relieving heat type were statistically significant,the curative effect is better than that of gastric bowel relieving heat effect.See table 3.4 after the team:the treatment group BMI was 36.34+/-4.64 before treatment,after treatment was 32.68+/-4.79,significant difference before and after treatment(P<0.05);The control group before and after the BMI comparison:the control group before treatment BMI was 35.71+/-5.35, after treatment of 35.43+5.11,there was no difference in the comparison before and after treatment(P>0.05);Group compared to control group after treatment BMI:significant differences in the BMI group and the control group after treatment(P<0.05).See table 4.5 compare two groups of blood fats,the treatment groop before and after the TG,TC,LDL-C,HDL-C:TG group before treatment for 3.96+/-0.87, after treatment for 1.92+0.72,before and after treatment had significant difference(P<0.05)ï¼›Treatment group after treatment before the TC was 4.48 +/-0.82 to 3.07+/-0.85,significant difference before and after treatment(P <0.05);Treatment group before treatment of LDL-C was 4.36+/-0.48 after treatment was 3.25+/-0.59,significant difference before and after treatment (P<0.05);Treatment group HDL-C was 0.67+/-0.13 before treatment, after treatment was 1.14+/-0.18,significant difference before and after treatment(P<0.05)ï¼›Control group before and after the TG,TC,LDL,HDL C-C:the control group before treatment TG for 4.02-0.99,after treatment for 2 to 59+0.64,no significant differences in the comparison before and after treatment(P<0.05);Control group TC was 4.53+/-0.76 before treatment,after treatment was 4.28+/-0.81,no significant differences in the comparison before and after treatment(P<0.05)ï¼›Control LDL-C was 4.38+ /-0.52 before treatment,after treatment was 3.34+/-0.57,no significant differences in the comparison before and after treatment(P<0.05);the control group before treatment of HDL-C was 0.66+/-0.16,0.87+/-0.14 after treatment,no significant differences in the comparison before and after treatment(P<0.05);the treatment group and control group after treatment of TG,TC,LDL-C,HDL-C:TG group and the control group after treatment with significant difference (P< 0.05); the TC group and the control group after treatment with significant difference (P< 0.01); the treatment group and control group after treatment of LDL-C(F> 0.05); the indiscriminate treatment group and control group after treatment HDL-C has a statistically significant difference (P< 0.01). See table 5Conclusion:1 removing qing xie stich with drugs is only has better weight loss drugs,antihypertensive,fall hematic fat action.2 acupuncture treatment of regulating lipid metabolism,and metabolic syndrome in removing the spleen kidney,qing xie phlegm tnrbidity as the therapentic principles,to achieve weight reduction,decompression,fall hematic fat action. |
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