Clinical Characteristics Of Cerebral Venous Sinus Thrombosis Analysis

Objective:To exploration and analysis of cerebral venous sinus thrombosis (cerebral venous sinus thrombosis, CVST), age, etiology, clinical features, radiological examination, diagnosis, treatment and prognosis in order to better understand the disease, help early diagnosis, treatment and prognosis. Methods:Select the First Affiliated Hospital of Xinjiang Medical University, Department of Neurology, April 2012 to October 2014 admitted to hospital 39 cases of intracranial venous sinus thrombosis in patients as research subjects, the clinical data were retrospectively analyzed and summarized intracranial venous sinus thrombosis risk factors, clinical features, imaging, treatment and prognosis. Results:39 cases of patients with CVST male to female ratio was 1.17:1, no significant gender differences in the age 20 to 49 years old were more common causes of morbidity and diverse, which is the cause of puerperal infection and who the most common clinical manifestations of non-specific, intracranial hypertension with headache is most prevalent. The clinical symptoms of secondary brain injury group than those without the substance of the brain parenchymal lesions weight, more headaches, seizures (P<0.05); and its short-term prognosis and no secondary parenchymal involvement CVST patients compared to less (P<0.05). Imaging is the main method of diagnosis of CVST, treatment of combined therapy. Conclusion: Intracranial venous sinus thrombosis causes complex and diverse, more common in young adult men and women may be the disease, non-specific clinical manifestations, headache, nausea, vomiting and other symptoms of intracranial hypertension, the most common, and most headache as the first symptom, most accompanied by substantial brain damage, but when accompanied by brain parenchymal lesions, severe symptoms, the prognosis is poor. Lumbar puncture, antinuclear antibody test for the diagnosis of a useful reference, platelets, blood D-dimer, fibrinogen, head CT, head MRI combined with MRV early diagnosis; treatment with combined therapy, early diagnosis and aggressive treatment of the prognosis of the disease is important.