The Long-Term Efficacy And Safety Of Different Sites Of Pacing In Right Ventricular

Objectives:The aim of this study was to compare the right ventricular outflow tract septal(RVOTS) pacing and right ventricular apical (RVA) pacing.To evaluate the long-term safety and safety in of different sites of right ventricular.Methods:1001 patients were daignosed bradyarryhthmia from Feb.2007 to Dec.2011. Group RVOTS (n=521) and Group RVA (n=480) who were paced in RVOT with active-fixation leads and right ventricular apex (RVA) with passive-fixation leads, respectively. This controlled clinical study compared the pacing parameters at implantation, week 1,months 1,6,12,18,24 after implantation, Echocardiography parameters at preoperative, moths 12,24 after implantation and complication.Results:Pacing threshold during implantation in Group RVOTS[(0.77±0.28)V] was significant higher than Group RVA[(0.53±0.17)V](P<0.05). The pacing threshold value between the two groups were not statistically significant differences during the follow-up periods. The RVOTS X-ray exposure time was significant longer than Group RVA (18.76±8.43 vs9.66±4.35) min(P<0.05). LAD, LVEDD, and LVESD were increase and LVEF were decrease in RVA group, but there was statistically significant differences in LVEF after moths 12. After months 24, the LAD, LVEDD, and LVESD’s increase and LVEF’decrease were statistically significant differences. The RVA group had no Cardiac perforation and RVOTS group had 7 Cardiac perforations, this difference had statistically significance(P<0.05).Conclutions:Right ventricular outflow tract septal pacing site is safe, and the pacing parameters were stable in long-term follow-up periods. But when the active-fixation lead fixed to the septum of RVOT and directed to the anterior or free wall maybe increased the risk of cardiac perforation.