| Part I:The value of 3.0T MR Diffusion-weighted Imaging in the Diagnosis and Staging of cervical carcinomaObjective:To evaluate the diagnostic and staging value of 3.0T MR diffusion-weighted imaging in the cervical carcinoma.Methods:The study includes histopathologically proved 48 cases of cervical carcinoma,7 cases of CIN and 10 cases of normal cervical tissue. All people underwent conventional MR sequences and diffusion-weighted imaging with b values of 0,500,1000 s/mm2 on 3.0 T MR. The detection rate of T2WI and of DWI with T2WI were calculated in cervical carcinoma respectively. Apparent diffusion coefficient value (ADC value) was measured in cancers and normal cervical tissues. Statistical difference was compared between two groups using one-way ANOVA. Morphological feature between cervical cancer and normal cervical tissue was compared. Morphological feature include contour, signal intensity (SI), size et al. Mean+standard deviation of ADC value of each FIGO staging was calculated and spearman correlation test was used to analyse the correlation between FIGO staging and ADC value of cervical cancer. The mean ADC value was measured in both metastatic pelvic lymph nodes and none-metastatic lymph nodes. Statistical differences were compared between the metastasis and none-metastasis using one-way ANOVA.Result:Within all of the 48 cases of cervical carcinoma,38 cases were detected on both T2WI and T2WI with DWI, with an equal detection rate of 79%. Within 38 cases of cervical carcinoma behind I a phase, the detection rate of T2WI and T2WI with DWI are equally 97%. ADC value of cervical carcinoma is (0.76±0.17) ×10-3mm2/s, significantly lower than that of normal cervical tissue(1.35±0.20) ×10-3mm2/s. The mean ADC value of metastatic lymph nodes is (0.877±0.033)×10-3mm2/s. The mean ADC value of none-metastatic lymph nodes is (0.877±0.033)×10-3mm2/s.There is statistically difference between them with P=0.00.Conclusion:There is no statistically difference between the detection rate of cervical carcinoma of DWI with T2WI and T2WI. MRI has poor diagnostic rate at cervical carcinoma in la phase and CIN. MRI may be more valuable in the diagnosis of cervical carcinoma behind Ia phase. ADC value has no relation with FIGO phase. DWI may increase the detection rate of pelvic metastatic lymph nodes in cervical cancer.Part II:The value of 3.0T MR Dynamic Contrast-enhanced Imaging in the Diagnosis of cervical carcinomaObjective:To evaluate the diagnostic value of 3.0T MR Dynamic Contrast-enhanced imaging in the cervical carcinoma.Methods:The study includes histopathologically proved 48 cases of cervical carcinoma,7 cases of CIN and 10 cases of normal cervical.All people underwent conventional MR sequences and dynamic contrast-enhanced sequences. The detection rates of T2WI and DCE with T2WI in cervical carcinoma were calculated respectively. Time-signal intensity curves (TIC) in cancers and normal cervical tissues were obtained and statistical difference was compared. Arterial relative signal intensity (ARSI) and maximum relative signal intensity (MRSI) in cervical cancer and normal cervical tissue were calculated respectively. Statistical differences were compared between the cancer and normal.Result:Within all of the 48 cases of cervical carcinoma,38 cases were detected on T2WI, with a detection rate of 79%, while 42 cases were detected on T2WI with DCE, with a detection rate of 87%. Within all of the 26 cases of cervical carcinoma,6 cases were proved to be rising type(accounted for 23%),9 cases were proved to be platform type(accounted for35%), while 11 cases were proved to be flow type(accounted for 42%). All of the 10 cases of normal cervical tissues are rising type. ARSI of cervical carcinoma is 2.28±0.09, MRSI of cervical carcinoma is 3.07±0.40; ARSI of normal cervical tissue is 0.85±0.31, MRSI is 2.41±0.38. ARSI between cervical carcinoma and normal tissue has significantly difference (P<0.05).Conclusion:The type of TIC offers diagnostic information in cervical carcinoma. The most significance difference is in the arterial phase of the whole dynamic contrast-enhanced imaging process. DCE is sensitive in demonstrating small tumors. |
PDF Full Text Request