Blood Cell Salvage And Autotransfusion’s Effects About Hepatitis Virus Load In Patients With Potral Hypertension

ObjectiveTo investigate the effects on hepatitis viral load of using cell salvageand autologous blood transfusion during devascularization and splene-ctomy in patients with portal hypertension and hepatitis cirrhosis effects,and the correlation between the changes of viral load and the amount ofblood autotransfusion.MethodCollected15cases of using cell salvage and autologous bloodtransfusion during devascularization and splenectomy in patients withportal hypertension and hepatitis cirrhosis in No.1Hospital of JilinUniversity from7.2014to3.2015, tested the HBV DNA quantitation byPCR enzyme-linked chemiluminescence methodbefore and3days afteroperation,and then comparative analysis the data.Result①15patients using autologous blood transfusion without hemolysisand fever②Preoperative and postoperative peripheral blood hemoglobin of15patients were (104.24.5) g/L and (113.93.7) g/L, postoperativehemoglobin obviously increased when compared with preoperative and the difference was significant (P=0<0.05).③Preoperative and postoperative HBV DNA quantification15patients were (277252.4147254.2) IU/ml and (211063.1133620.4)IU/ml, had no significant difference (P=0.435>0.05).④The change rate of HBV DNA quantification was not related toautotransfusion volume, and the correlation coefficient is-0.713.Conclusion Using cell salvage and autologous blood transfusion duringdevascularization and splenectomy in patients with portal hypertensionand hepatitis cirrhosis is safe and effective,.It could significantly improvethe postoperative Hb level and reduce the amount of blood productrequirements. It didn’t have significant effects on the viral load,and thechange rate of HBV DNA quantification was not related toautotransfusion volume, but there still need a large sample,randomizedand prospective studies to support this conclusion, and also needcontrolled trials to excluded splenic blood’s influence.