Analysis Of Risk Factors And Pathogens Of Maintenance Hemodialysis Complicated With Pulmonary Infection Resistance

Objective Analysis the risk of pneumonia in patients with maintenance hemodialysis in our hospital factors, pathogens and clinical treatment, provide the basis for clinical treatment of chronic renal failure complicated with pulmonary infection, improve patient quality of life and survival rate.Methods Retrospective analysis of2010April to2013April in380cases of clinical data of patients with maintenance hemodialysis therapy in our hospital; According to whether the patients with pulmonary infection were divided into infection group and non infection group, and the relationship between the relevant differences between two groups were compared;And the infection were the result of sputum culture of bacteria drug sensitive test and application of antibiotics.Result Analysis of our hospital380cases of hemodialysis patients, pulmonary infection in78cases, the infection rate was20.5%. Statistical analysis revealed that age, dialysis adequacy, hemoglobin, total protein, albumin and diabetic nephropathy complicated with pulmonary infection. According to the results of sputum culture in infection group,78cases of maintenance hemodialysis patients with pulmonary infection were78sputum specimens of sputum examination, inspection rate of100%, a total of28 cultured strains of pathogenic bacteria, sputum pathogen detection rate of35.9%. Among the19G-strains, accounting for67.9%, G+accounted for10.7%of3strains,6strains of fungi, accounted for21.4%. Analysis of drug resistance of pathogenic bacterium found G+to imipenem, vancomycin, rifampicin, tetracycline resistance minimum,G-bacteria to piperacillin tazobactam resistance minimum, Fungal to fluconazole, amphotericin B drug resistance minimum. Analysis of clinical efficacy treatment with antibiotics alone, Beta lactam on uremic lung infection has the highest efficiency, up to86.1%, followed by quinolones, efficiency is58.3%,again for macrolide, efficiency is57.1%. But P>0.05,there is no significant difference between three person effect. Combined treatment using antibiotic treatment, the total effective rate(95.7%) higher than single use of antibiotics(81.8%), and P<0.05, there were obvious differences in the efficacy. Conclusion:reasonable use of antibiotics has important implications for the treatment of uremia pneumonia.Conclusion Old age, anemia hypoproteinemia,inadequate dialysis, diabetes nephropathy is the risk of pneumonia in patients with maintenance hemodialysis factors. Hemodialysis is associated with lung infection, should be the rational use of antibiotics.