Analysis Of Brain Arteriovenous Malformations Bleeding Factors

Background:Intracranial hemorrhage in BAVM is life threatening clinical entity. Currently the risk factors of BAVM bleeding still need to be further defined.Objective:To analysis and summarize the risk factors of BAVM bleeding.Methods:In this retrospective study, we collect the clinical data of84diagnosed BAVM patients from the April2013to the March2014at the second Affiliated Hospital of Zhejiang University. Factors affecting BAVMs like gender, age, initial presenting symptom, location and size of lesion, the number of feeding arteries, draining veins, association with other intracranial vascular abnormalities were collected. All the mentioned parameters were analyzed with chi square test. Parameters with significant results were evaluated using logistic regression.Results:There were84patients initial diagnosed brain arteriovenous malformations in the second Affiliated Hospital of Zhejiang University from the April2013and the March2014, including58males and26females, the ratio was2.23:1; ranged from3.66years to68years old, the median patient age was31years and the average age was35.25±15.65years old, the20-30-year-old was the peak, occupying27%of total number. The symptoms of hemorrhage mainly included headache with vomiting, disturbance of consciousness, and focal neurological deficit. And in the non-bleeding group, the symptoms contained headache with dizziness, limb weakness, sensory disturbance, epilepsy. The29.76%of BAVM located at infratentorial region. The diameter of BAVM was less than3cm for most part. The Spetzler-Martin grading of I-VI was21.43%,25%,28.57%,16.67%,8.33%respectively. The21.4%of the patients (18cases) were accompanied by other intracranial vascular abnormalities, in which aneurysm was frequent. One to2feeding artery is common in BAVM, but3or more feeding arteries are relatively uncommon; the71.42%of the BAVM were drained by superficial veins,25.00%to the deep, and3.57%of patients (3cases) had both draining veins.Conclusions:BAVM is common in young people, the incidence of male is one time more than female. Most of BAVM located at superficial brain.There are commonly1to2feeding arteries. The draining veins are often superficial. About1/5of patients are accompanied with other intracranial vascular abnormalities. BAVM maximum diameter of less than3cm, with deep veins are BAVM bleeding risk factors.