The Analysis Of The Middle Cerebral Artery Aneurysms Hemodynamics Numerical Simulation And The Breakdown Point Of The Findings In Operation

Experimental background:The most common cause of subarachnoidhemorrhage(SAH)is the rupture of Intracranial aneurysm which leading tocerebrovascular disease mortality for about25%.The most common ofintracranial aneurysm type is Middle cerebral artery aneurysm,which oftengenerating on the artery bifurcation,When the aneurysm breaking,thehematoma in the brain oppress the nerve and brain.The result caused the heavypsychological and economic burden for patients and their families.For now,thearticles of experimental Aneurysm rupture for local blood flow analysis isless.This study determine rupture location of the middle cerebral arteryaneurysm visually,analysing and comparing with blood flow dynamics byThree-dimensional numerical simulation which providing objective evidencefor the clinical treatment of aneurysms.Objective:Through the simulation of MCCAs hemodynamics andobservation of aneurysm rupture location with the microscope,we try toanalyse the relevant hemodynamic parameters.Materials and Methods:Collected35patients with intracranialaneurysms of Sino-Japanese Friendship Hospital of Jilin University fromSeptember2011to2014September that treatment by early surgical(within72 hours after onset),Of which21males and14females,emal:female=3:2,aged39to64years old,with an average age of48.00±6.30years.35cases patients areall middle cerebral artery aneurysm;mproved Fisher grade1:5cases,2:12cases,3:16cases,4:2cases;Hunt-Hess grade level,Ⅰ4cases,Ⅱ13cases,Ⅲ15cases,Ⅳ2cases,Ⅴ1case.Based on its3D-CTA imaging data,the useof computers and related fluid dynamics software to build geometric models ofaneurysms,aneurysm rupture location and hemodynamic simulation,controlintraoperative microscope analysis of the correlation of aneurysm ruptureblood Hemodynamic parameters.Results:1.The patients were divided into two groups by MCCAs breakposition after surgery.One group(Type I):the aneurysm rupture is located in thesidewall(24cases);the other group(Type II):the aneurysm rupture is located atthe bottom of the aneurysm(11cases).2.The patients were divided into two groups by the hemodynamiccharacteristics:one group:the rupture located the turning point(27cases),including the bottom of aneurysm rupture(3cases);the other Group therupture located aneurysm at the bottom(11cases).3.17cases of patients with children tumor of the MCCAs,the rest18casesof patients,no children tumor,and20patients with tumor in13cases of type Aaneurysm,7cases of type B the aneurysm.4.Type A aneurysm has large wall shear stress on the rupture point.AndType B aneurysm has little wall shear stresson the rupture point. Conclusion:In this study,we established intracranial aneurysm modelsuccessfully which based on3D-CTA,and simulated hemodynamic intracranialaneurysms.The resulting number of hemodynamic parametersmultivariate,multi-angle comprehensive analysis of patients for the clinicaltreatment of arterial aneurysms provides a theoretical basis,The method issimple,the use of a short time,good repeatability.By MCCAs break at thehemodynamic analysis,with the completion of intraoperative aneurysm clipsdirectly observed under the microscope aneurysm rupture location combine tohemodynamic study provides a new direction...