The Impact Of Serum Amh And OHSS By Modified Yangjingzhongyu Prescription For The Non Obese PCOS Patients Of IVF-ET

Objective: The modified yangjingzhongyu prescription on the incidence of ovarian hyperstimulation syndrome(OHSS) clinical effects for the non obese polycystic ovary syndrome(PCOS) patients of in vitro fertilization and embry transfer(IVF-ET), and analyze its mechanism of action. To explore the serum AMH predictive value of OHSS.Methods: Conform to the selection criteria of 60 cases of the non obese PCOS patients, randomly divided into the control group and the treatment group, 30 cases in each group.Two groups all use gonadotropin-releasing hormone agonist(GnRH-a) long plan.The treatment group given modified yangjingzhongyu prescription on gonadotropin, while the control group not taking. All the research object to collect serumthe on Gn days and HCG day, compare two groups of patients before and after treatment of traditional Chinese medicine symptom integral,the Gn days and HCG day serum AMH, E2, P levels,the Gn total,the Gn days, the average daily of the Gn, eggs number, fertilization number, high quality embryos and moderately severe OHSS incidence, Comparison of OHSS group and non OHSS group serum AMH levels on the Gn days and HCG day.Results: 1.Treatment group after treatment of liver and kidney Yin deficiency syndrome improve better than control group(P<0.05).2.Treatment group the AMH level of the HCG day was lower than the control group(P<0.05), but the serum levels of E2 and P there was no difference(P>0.05).3.Treatment group the Gn total,and the average daily of the Gn significantly less than the control group(P<0.05),but the Gn days was no statistically significant difference(P>0.05).4.Number two groups received the eggs and fertilization is no difference(P>0.05), the treatment group of high quality embryo number is better than the control group(P<0.05).5.The relation about incidence of OHSS.The treatment group(6.6%) was significantly lower than control group(13.3%)(P<0.05). 6.Theserum AMH level on the Gn days and HCG day. the comparison between groups and temporal-self comparison, differences were statistically significant(P<0.05).Conclusion: The modified yangjingzhongyu prescription can effectively improve liver and kidney yin deficiency type of the non obese PCOS patients clinical symptoms, and improve quality embryos. The modified yangjingzhongyu prescription by reducing the day of HCG serum AMH level so as to reduce the incidence of OHSS.The GN day and the day of HCG serum AMH level can be used to predict the non obese PCOS patients with moderately severe OHSS.