Application Of Sodium Potassium Magnesium Calcium And Glucose Injection During Cesarean Section

Objective: To explore the clinical effects of sodium potassium magnesium calcium and glucose injection compared with lactate Ringer’s solution during cesarean section.Methods: 120 cases of cesarean section were randomly divided into lactate Ringer’s solution group(R group) and sodium potassium magnesium calcium glucose injection group(L group), and the maternals were full-term primiparas with single pregnancy, age 21-32 years old, height 155-171 cm, weight 63-85 kg, ASA I-II grade, 60 cases in each group. Lactated Ringer’s solution and sodium potassium magnesium calcium glucose injection were infused respectively in two groups after entering in the operation room, the initial infusion rate was 15 m L/kg/h, then it was changed into 10 m L/kg/h when 500 m L fluid was infused. American spacelabs healthcare systems were used to monitor vital signs, and the immediate vital signs were taken as the basic values.All maternals were selected for subarachnoid block anesthesia, with local anesthetic of 0.5% bupivacaine 1.5-2.0 m L.The maternal’s heart rate(HR) and mean arterial pressure(MAP)were observed at the four time points,which were before anesthesia(T1), prostration after drug injection in spinal canal(T2), after delivery of fetus(T3) and at the end of operation(T4).The neonatal’s Apgar score, preoperative and postoperative parturient analysis of arterial blood gas values, umbilical arterial,venous blood gas values after subtracting umbilical cord, amount of bleeding during operation and complications related to liquid transfusion were also recorded.Results: Firstly, there was no statistical difference on maternal’s HR, MAP, the amountof bleeding during the operation, neonatal’s Apgar score in two groups(P>0.05). Secondly, there was no statistical significance on blood gas analysis of values of p H, BE, PCO2, lactic acid(Lac) in two groups(P>0.05).Thirdly, there was no statistical difference on electrolyte values(Na+, K+, Ca2+), neonatal umbilical arterial and venous blood glucose(Glu) in two groups(P>0.05), there were no significant difference between groups of maternal blood glucose(P>0.05), but the difference was statistically significant in the same maternal’s group(P<0.05).Maternal’s postoperative blood glucose levels were higher than those before operation.Lastly, there was no statistical significance on the incidence of chill, fever, dizziness, headache, itching,arrhythmia in the process of transfusion(P>0.05).Conclusion: Similar with lactate Ringer’s solution, there is little difference on maternal and neonatal internal environment and volume expansion with sodium potassium magnesium calcium glucose injection, and it can be safely and effectively used duringcesarean section with appropriate dose.