Closed-loop Type Muscle Relaxant Injection For Elderly Patients With General Anesthesia Recovery Period

Objective: Compare the closed-loop muscle relaxant time intravenousinfusion and points of muscle relaxant drugs in elderly patients withlaparotomy curative effect in clinical application Surgery in elderlypatients with general anesthesia in the safest and the most reasonablemuscle relaxant drug delivery mode.Methods: Choose from November2013to November2014, theAmerican society of anesthesiologists (ASA) Ⅱ~Ⅲ level60patientsundergoing elective in elderly patients with colon and rectal surgery. allpatients were filtered by incorporating and exclusion criteria.double-blindrandomized composition times intravenous injection group (I),continuous closed-loop input method (Ⅱ). two groups all use the sameanesthetic induction and maintenance.Part I give maintain convenientlyatracurium dosage,Ⅱ group by the closed-loop muscle relaxant injectionsystem for conveniently atracurium.two groups of patients withpostoperative don’t use muscles antagonist medicine, observe andcompare two groups of muscles in patients with spontaneous recovery.using four clusters stimulate the ulnar nerve by thumb adduction musclecontraction in response to monitor TOFr value. To observe and recordthe muscle relaxant monitoring value TOFr back to25%of the time (T1), back to50%of the time (T2), the recovery time (T3), restore to75%to90%(T4) continuously. To record the extubation time (t1) and head orlimbs of5s time (t2), the PACU time (t3), the total drug dose and twogroups of patients recovery sedation scores (Ramsay scoring criteria)score.Results: Two groups of patients’ age, weight and grade of endotrachealintubation, general data, such as the operation time is not significant.Induction of before and after extubation two groups of patients withhemodynamic indexes (systolic pressure, diastolic blood pressure, heartrate), respiratory frequency, tidal volume and blood oxygen saturationcompared with preoperative no statistical difference (P>0.5). the musclerelaxant monitoring value TOFr back to25%of the time (T1), back to50%of the time (T2), the recovery time (T3), restore to75%to90%(T4)continuously。Comparison between groups was statistically significant (P<0.05). head or limbs of5s time (t1) and extubation time (t2), PACUtime (t3) and total drug dosage were statistically significant (P <0.05).two groups of convalescence sedation scores (Ramsay scoring criteria)there was no statistically significant difference of score.Conclusion:1、The closed-loop muscle relaxant infusion compared with splitintravenous infusion of muscle relaxant，recovery time in the elderlypatients with laparotomy and PACU time significantly shortened. 2、The closed-loop muscle relaxant infusion compared with splitintravenous infusion of muscle relaxant，on the amount of medication andmuscle relaxants decreased significantly.3、Closed-loop infusion of nondepolarizing muscle relaxant easier tocontrol，more convenient in management of anesthesiologists.