| The trend of increasing prevalence for asthma and airways symptoms in China duirng the last decades has been accepted widely, especially the prevalence in children ashtma. Results of National Cooperation Group on Childhood Asthma in China showed that Shanghai children, aged 0~14 years old, suffer asthma most in both two surveys in China, its prevalence is about 1.2 times higher in 1990 than that in 2000. And according to the report of SCDC(Shanghai Municipal Center for Disease Control & Prevention) in Augest, 2006, the prevalence of asthma was 5.92% for children aged 6~14 years old which is about one times higher than that in 2000. Obviously, this period is too short for gene to change, so it can?t depend on the gene only to explain the fast development of asthma during such a short period, more attention should be focused on the environmental factors and the association between them.Human beings spend much more time indoors than outdoors. So the quality of indoor environment means a lot to human health which may cause the direct effect. Because of its special location which is near both river and sea, and its special north subtropical monsoon climate, shanghai indoor environment has more dampness indicators like mold, dampness spot, water damage and consendation on window than most cities in China which can cause physical, chemical and biological influences and increase the risk of cough, wheezing and asthma of the residents.As part of CCHH(Chinese, Children, Homes, Health) study, this study focused on the association between dampness indicators and asthma symptoms as well as the multifactor effects of dampness to children. To get enough data, a cross-sectional study was started in 88 kindergartens of 6 districts in Shanghai. 15266 Chlidren aged 1~8 years old from 5 districts except Yangpu district were analyzed in this study. It was found that the prevalences of wheezing, dry cough, asthma and croup were 28.0%, 17.0%, 9.3% and 5.8% respectively. And the dampness indicators of mould, dampness spot, water damage in the last 12 months, water damage before one year and condensation on window were 7.9%, 15.2%, 8.6%, 9.4% and 54.9% respectively. These data shows that both the children health and indoor dampness are worrying.Based on Logistic regression and crossbats in SPSS 17.0, the related factors of children asthma would be listed one by one as well as the colinearity test among these factors would be taken to build up the final Logistic regression model for better analyzing the association between dampness and asthma symptoms. This final Logistic regression model would consider the multifactor effects of dampness to make its effect on children asthma clear. It shows that the inheritance is the main reason for the children asthma. And the effect of homedamoness disappeared after the multifactor effect of home dampness. However, the home dampness like mold, dampness spot and condensation on window can increase the risk of wheezing, dry cough and croup of children. And compared with the inheritance, the influence of dampness indicators on children asthma equals about 18%~74% inheritance effects on children asthma. |
