Effects Of Different Doses Of Sufentanil Induced On BIS Value Of Video Laryngoscope Tracheal Intubation

Objective:To study the effects of different doses of sufentanil on hemodynamics induced by video laryngoscope and BIS, to explore the appropriate dosage of sufentanil for video laryngoscope tracheal intubation.Methods:60 patients with nasal endoscopic surgery, according to the American society of anesthesiologists(ASA), the person that the illness class is Ⅰ ~ Ⅱ age 25 to 55 years old,height 160 ~ 175 cm, weight 54 ~ 73 kg, and no preserving renal complications. On preoperative evaluation of the airway. Selection of Mallampati airway hierarchical classification in patients with grade I ~ III. Randomly divided into A, B, C three groups,each group 20 cases. Group A(sufentanil 0.2μg/kg) and group B(sufentanil 0.4μg/kg),group C(fentanyl 2μg/kg). All surgical patients after home, open upper limb venous pathway, electrocardiogram, pulse, blood oxygen saturation, hemodynamic indexes such as blood pressure, and electrical double index(BIS) values. Vein order giving patients imidazole stability and 0.06 mg/kg; Sufentanil for A 0.2μg/kg group A and group B sufentanil for A 0.4μg/kg, give fentanyl group C 2μg/kg; Etomidate 0.3mg/kg;Vecuronium bromide 0.1 mg/kg; Oxygen masks to 3 l/min, hand control breath, airway pressure maintaining 15-20 cmh2 o levels and stay vecuronium bromide after work, use Shikani endotracheal intubation. Monitor and record the T0 before anesthesia induction, T1(endotracheal intubation before), T2(when endotracheal intubation), T3(1 minute) after intubation, T4(3 minutes), T5(5 minutes) electrical double frequency index(BIS),blood pressure(MAP), heart rate(HR).Results:1.Three groups of patients with heart rate HR comparison, compared with T0 T1decreased(P < 0.05), low level comparison between group A and group decreased,compared with B and C group was statistically significant(P > 0.05); Compared with T0 three groups of T2, T3, T4,T5 time HR has no obvious difference(P > 0.05);2.Three groups of patients with blood pressure MAP comparison, compared with T0T1 decreased(P < 0.05), compared between group A and group fell by less, compared with B and C group was statistically significant(P > 0.05); Compared with T0 three groups of T2, T3, T4,T5 time point MAP has no obvious difference(P > 0.05);3.Compared with T0, the BIS value after induction of three group were decreased,with statistical significance(P < 0.05), compared each point in time no statistical significance between groups(P > 0.05).Conclusion:1.Different concentrations of sufentanil and fentanyl anesthesia induced joint visual laryngoscope endotracheal intubation can effectively relieve trachea intubation stress reaction, but sufentanil more effective than fentanyl.2.Different concentrations of sufentanil anesthesia induced joint visual laryngoscope endotracheal intubation, all can meet clinical needs appropriate anesthesia depth, but small doses sufentanil safer and stable.3.Small doses sufentanil mu(0.2μg/kg) induction of general anesthesia combined visual laryngoscope endotracheal intubation can at the same time, guarantee the stability of hemodynamics can reduce the stress reaction of endotracheal intubation, ensure adequateanesthesia depth, is the visual laryngoscope ideal induction dose of endotracheal intubation.