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Clinical Efficacy Of Neoadjuvant Chemotherapy In Gastric Cancer Used DCF Programs And FOLFOX6 Program

Posted on:2016-11-18Degree:MasterType:Thesis
Country:ChinaCandidate:S CaoFull Text:PDF
GTID:2284330479975075Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: To evaluate the effect of operation in patients with gastric cancer D C F scheme and FOLFOX6 scheme. Methods: Taking FOLFOX6 and DCF regimen for patients with effective chemotherapy to evaluate the efficacy of chemotherapy. Results: The clinical control rate of FOLFOX6 group and DCF group are 38.9% and 70.0%,(P < 0.05). Comparison of the two chemotherapy groups,DCF groups can more effectively reduce the staging,the difference is statistically significant(P <0.05). Because of small sample size, the two groups of radical resection rate and postoperative complications do not differ significantly, the difference is not statistically significant(P >0.05). Conclusion: Patients should be evaluated for gastric surgery and neoadjuvant chemotherapy, to improve the quality of life in patients with an effective way.Within the sample prescribed,In clinical control rate and lowering of the effective rate, DCF scheme is more obvious than FOLFOX6 program, but DCF scheme has more toxic,which inspired us in the choice of chemotherapy, considering the clinical effects should also take into account the patient’s tolerance.
Keywords/Search Tags:Neoadjuvant chemotherapy, Assessment, Quality of life, Toxicity Combination therapy
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