Relevance Between The MRI Parameters And Cartilage Injury Of Patellofemoral Pain Syndrome Patients

Objective:There are few research on the correlation of patellofemoral pain syndrome(PFPS) and the the cartilage injury till now. It’s urgent to develop a method to evaluate the morphological abnormalities of PFPS and articular cartilage injury accurately, noninvasively and effectively, and to provide a simple qualitative and quantitative indicator for curing PFPS and prevention the patellofemoral arthritis. Methods:By comparing 8 parameters(ISA ratio, PTA, SA and TA, BO, LTI, patellofemoral width, patellofemoral thickness) measuring by MRI between 49 PFPS patients(55 knees) withnormal patellar arrangement patients with no cartilage injury to determine whether there is difference between PFPS patients and the control group. Then T2-Mapping was conducted both two group. The patellofemoral arthritis patients waseliminated and noly patients with mild cartilage damage were selected to measure their internal and external femoral condyle,T2 relaxation of patella cartilage andeight parameters by MRI.The statistic canonical correlation analysis method was used to the correlation between patellofemoral joint parameters and cartilage damage. Results:After comparing all MRI parameters of PFPS and the control group, it was found that five parameters(ISA, PTA, SA and TA, LTI) was statistically difference(P < 0.05), and the rest parameters(BO, patellar patellar width, patella thickness,Ratio of width and thickness) have no statistical significance. Two comprehensive variables were usedto reflect furtherly the overall relevance between the patellofemoral joint related parameters with patellofemoral articular cartilage damage. The first set typical variables V1 =-0.80×lateral femoral condyle-0.262×medial femoral condyle-1.110×patella,U1=-0.701×ISA-0.760 ×SA-0.213×TA-0.371× LTI-0.352×PTA. Conclusion:In MRI measurement parametersof patellofemoral joint, ISA ratio, PTA, SA and TA, LTI can be used as the objective index of PFPS. Patellofemoral joint parameters of the ISA and SA can be employed as PFPS objective diagnostic indicators for cartilage early injury. It also is impersonal indexes for evaluation of therapeutic effect and choosing the right time for articular cartilage injury treatment.