| Objective: To evaluate the value of CT spectral imaging of diagnosing lung cancer and metastatic lymph nodes and differing different pathology type metastatic lymph nodes.Materials and Methods: Patients with lung cancer and metastatic lymph nodes proved by pathological findings underwent double-phase enhanced CT scan using GSI(gemstone spectral imaging) mode from Dec 2013 to Dec 2014. Seventy–four patients(40men, 34 women, age range: 25-76, mean age: 58) were included into the study. All patients were separated into groups as follow:(1)All the cases were divided into two groups: metastatic lymph nodes group(including 23 squamous carcinomas, 28 adenocarcinomas and 5 small cell lung carcinomas) and normal lymph nodes group(18cases);(2)Metastatic lymph nodes group included 23 cases squamous carcinomas, 28 cases adenocarcinomas and 5 cases small cell lung carcinomas, respectively. GE gemstone CT(Discovery CT750 HD) GSI mode were used and scans were started automatically30 s and 90 s after the contrast agent were injected. According to CT spectral imaging, CT values at different single energy, slope rate of spectral curve, water concentration, iodine concentration in both early and later phase were measured and calculated respectively using GSI Viewer software. Analysis of variance, LSD-t test, t test and correct t test were performed to compare the spectral parameters.Results:(1) There were significant differences in each spectral parameter between metastatic lymph nodes group and normal.(2) There was no significant difference in water concentration among three groups in both phases. There were significant differences in the slope rate, iodine concentration either among three groups.Conclusions:It is helpful to diagnose the lung cancer and metastatic lymph nodes using qualitative and quantitative analysis with CT spectral imaging. It is useful to distinguish different pathology type lung cancer and their metastatic lymph nodes with CT spectral imaging. |
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