A Comparative Study Of The Efficacy Of Non Segment Elevation Acute Myocardial Infarction Treated With Combined Low Molecular Weight Heparin Calcium In The Treatment Of Patients With Acute Non ST Segment Elevation Myocardial Infarction

Objective:To analyze the treatment results of tirofiban combined with low molecular weight heparin for acute non-ST segment elevation myocardial infarction disease treatment.Methods:Eighty six patients of acute non-ST segment elevation myocardial infarction acquired from June 2013-December 2014 received hospital treatment. The patients were randomly divided into two groups:Group A including 40 patients and group B including 46 cases. Low molecular weight heparin injection was administrated subcutaneously in Group A; Tirofiban hydrochloride combined with low molecular weight heparin was used in Group B. Comparative analysis of the treatment results of patients in the two groups regarding main adverse cardiac events NT-proBNP, Left ventricular ejection fraction (LVEF) and platelet count during the three-month treatment period.Results:The mortality rate, recurrent myocardial infarction rate and intractable angina pectoris rate in Group A patients was 5.0%,7.5% and 7.5%, respectively. While in the B group patients, the rate was 0%,2.2% and 0%, respectively. The MACE rate was significantly lower in Group B. Compared with Group A, NT-proBNP levels measured in group B were remarkably lower while LVEF was significantly improved (P<0.05). The moderate and serious hemorrhage rates between Group A and B were not significantly different. The difference of platelet count of the two groups was not statistically significant.Conclusion:Tirofiban combined with low molecular weight heparin treatment for acute non-ST segment elevation myocardial infarction significantly decreased the MACE rate, improved the myocardium function. The moderate and serious hemorrhage rates were not increased. The treatment modalities can be widely used in clinical practice.