Correlation Analysis Of Clinical And Biochemical Characteristics Of Polycystic Ovary Syndrome Patients With Phlegmand Blood Stasis Mutual Junction

Objective:Through the study of clinical and biochemical characteristics of polycystic ovary syndrome (PCOS) with phlegm and blood stasis mutual type patients, highlight the main clinical and biochemical characteristics of polycystic ovary syndrome with phlegm and blood stasis mutual.Make analysis correlation to understand their individual correlation of clinical and biochemical factors, providing a basis for further research and treatment of disease.Method:Bring to 125 cases patients which according to the PCOS diagnostic criteria and phlegm and blood stasis type of TCM as the research object in heilongjiang university affiliated hospital of Chinese medicine. Make analysis correlation to its clinical characteristics (age, menarche age, height, weight, waist circumference, hip circumference, hairy score, acne, acanthosis nigricans, excessive fat, etc.) and biochemical index (six sex hormone, three androgens, glucose tolerance test and insulin release test, blood lipid seven, etc.) and use SPSS19.0 for statistical analysis.Results:1.Menarche age and AND (r=0.415, P<0.05) of PCOS with phlegm and blood stasis mutual junction was moderate positive correlation.2.For patients of PCOS with phlegm and blood stasis mutual junction,weight with T (r=0.447, P<0.05), FAI (r=0.452, P<0.05) of PCOS with Phlegm and blood stasis mutual junction were moderate positive correlation,with SHBG (r=0.578, P<0.01) was moderate negative correlation, with 30minG (r=0.525, P<0.01) was moderate negative correlation, with 30 minINS (r=0.453, P<0.05) was moderate positive correlation. BMI with FAI (r=0.489, P<0.05) was moderate positive correlation, with SHBG (r=0.600, P<0.01) has a strong negative correlation. Waist circumference with T (r=0.442, P<0.05)、FAI (r=0.451, P<0.05) were moderate positive correlation, with E2 (r=0.439, P<0.05)、SHBG (r= 0.436, P<0.05) were moderate negative correlation, with FINS (r=0.417,P< 0.05) was moderate positive correlation. Hip circumference with T (r=0.421, P<0.05) was moderate positive correlation, with SHBG (r=0.382, P<0.05) was moderate negative correlation. WHR with PRL (r=0.430, P<0.05)、FAI (r=0.431, P<0.05) were moderate positive correlation.3.For patients of PCOS with phlegm and blood stasis mutual junction,systolic blood pressure with PRL, T, FAI were positively correlated, dependency with PRL (r=0.599, P<0.599) and T (r=0.566, P<0.01) were moderate, with FAI (r=0.708, P<0.01) was a strong positive correlation. Diastolic blood pressure with PRL (r=0.417, P<0.05) and FAI (r=0.474, P <0.05) were moderate positive correlation.4.For patients of PCOS with phlegm and blood stasis mutual junction,LDL with 120 minG (r=0.428, P<0.05) was moderate disease related. APOA with FPG (r=0.415, P<0.05)、HOMA-IR (r=0.438, P<0.05) were moderate negative correlation. APOB with 120 minG (r=0.438, P< 0.438)、180 minG (r=0.414, P<0.05) were moderate positive correlation. APOB/APOA with FPG (r=0.417, P<0.417)、120 minG (r=0.445, P< 0.445)、120 minINS(r=0.451, P<0.451)、HOMA-IR (r=0.477, P<0.05) were moderate positive correlation. Lipoprotein-a with FPG (r=0.452, P< 0.05) was moderate positive correlation.Conclusion:1.Late menarche age may be a risk factor for high androgen.2.Obesity was the main characteristics of patients of PCOS with phlegm and blood stasis mutual junction. Obesity may be the important reason for the patients with elevated androgen, and might result in lower estrogen levels,and affect the incidence of chance for impaired glucose tolerance and diabetes.3.High blood pressure increases with hyperprolactinemia and high androgen levels maybe have closely related.4.Dyslipidemia increased have closely related to the risk of the high level of insulin resistance and abnormal glucose metabolism.