Investigation Of Early Micro-feeding In Very Low And Extremely Low Birth Weight Infants

Objective:Trace cases of early neonatal feeding of a hospital in Changchun for two years within the data analysis and summary about early micro-feeding, To explore the feeding interval time of early micro feeding and the related factors of the feeding intolerance in early micro feeding, and to provide guidance and reference for clinical treatment and nursing of premature infants.Methods:This study was based on the study of VLBWI and ELBWI in neonatal pediatric department of a top three hospital in Changchun fromnovember 2013 to november2015, to collect the general information and the data of hospitalized children in accordance with the inclusion criteria. According to birth weight, 1001g~1250g,1251g~1500g, <1000g is divided into BW1, BW2, BW3 groups; according to the gestational age <28 weeks, 29~30 weeks, 31~32 weeks is divided into GA1, GA2,GA3 groups, according to whether or not tolerated by feeding into FI, FT groups, after comparing the three groups, the data were analyzed by using Excel software and SPSS17.0 software for statistical analysis.Result:1.GA1,GA2,GA3 significantly different between the three groups of enteral nutrition start time(P<0.001), The smaller the gestational age is, the later the enteral nutrition begins(GA1,GA2,GA3 enteral nutrition start time was15.38±5.49,9.37±4.54,5.51±2.97);BW1,BW2,BW3 between the three groups of enteral nutrition start time of a significant difference(P <0.001), the smaller the birth weight,the later the enteral nutrition starts(BW1,BW2,BW3 enteral nutrition starttime was 15.50±5.33,9.42±4.52,5.44±3.18), among SGA,AGA,LGA three enteral nutrition start time were no significant difference(P> 0.05).2. In the first two weeks after birth, according to the median of the number of times of daily feeding group, draw the line chart found that there is a certain regularity.3.GA1,GA2,GA3 among the three groups in hospitalization, the recovery time of birth weight, body weight up to 1500 g time there is a significant difference(P<0.001),the smaller the gestational age, the longer the length of stay, the longer the time of birth weight, the longer the body weight of 1500g;BW1,BW2,BW3 between the three groups in hospital time, body weight up to 1500 g time has significant difference(P<0.001), there were statistically significant differences between the three groups in the time of recovery of birth weight(P<0.05) among the three groups, The longer the birth weight, the longer the length of stay, the longer the body weight of 1500 g, the longer the time of birth weight. SGA, Aga, LGA between the three groups of hospital stay, weight of 1500 g time has no significant difference(P>0.05). Body weight group,gestational age group, and the relationship between gestational age and body weight of the weight loss of each group had no statistical difference(P> 0.05).4. The rate of feeding intolerance between the groups was no significant difference, in addition to birth weight group,the duration of feeding intolerance between groups has no significant difference(P>0.05).5. sexual distinction, birth weight, gestational age, mode of delivery, the mother has pregnancy-induced hypertension, infection or not, whether 32 factors were analyzed by univariate chi-square test analysis showed patent ductus arteriosus,invasive mechanical ventilation, RDS(respiratory distress syndrome), using PS(pulmonary surfactant), perinatal infections, pregnancy-induced hypertension,neonatal anemia in the feeding intolerance group and feeding tolerance group, the difference was statistically significant(P<0.05). The univariate analysis results in P<0.05 variables included in the logistic regression model for multivariate analysis,the results suggest: perinatal infection, neonatal anemia and maternal pregnancyinduced hypertension may be the risk factors of feeding intolerance.Conclusion:1. Early micro feeding time is inversely proportional to gestational age and weight.2. Early trace feeding of preterm infants first increase the number of feeding,beginning of the increase in feeding amount after reaching 8 times a day, in this mode,the number of daily feeding of children born with the growth of the number of days stepwise growth.3. Early trace feeding does not increase the probability of feeding intolerance and the incidence of nutrition related complications.4. Perinatal infection 、 neonatal anemia and pregnancy induced hypertension syndrome are the risk factors of feeding intolerance.