Nonsteroidal anti-inflammatory drugs are widely used to diminish inflammation and pain. According to the ability to inhibit cyclooxygenase, they are divided into three categories. In recent years, lots of researches find that they have certain effect on cardiovascular events. Cyclooxygenase-1 selective inhibitors play a good role in secondary prevention in subjects with cardiovascular disease, and are still controversial in primary prevention.cyclooxygenase-2 selective inhibitors mostly increase the risk of cardiovascular events.Most kinds of non selective cyclooxygenase inhibitors also increase the risk. This view focuses on the research progress of the relationship of non steroidal anti-inflammatory drugs and cardiovascular events. |