Impact Of Serum Bilirubin Level On Patients Undergoing Pancreaticoduodenectomy

Objective:Pancreaticoduodenectomy is a very complex and dangerous surgery to patients with malignant obstructive jaundice. A retrospective study was carried out on 60 patients with obstructive jaundice who met the inclusion criteria for pancreaticoduodenectomy were treated from January,2012 to December,2014, QiLu Hospital of Shandong University. To analyze the effect of Serum Bilirubin Level in Patients Undergoing Pancreaticoduodenectomy. To explore the preoperative serum bilirubin levels should be controlled. To guide the clinical application of preoperative biliary drainage.Methods:A retrospective study was carried out on 60 patients with obstructive jaundice who met the inclusion criteria for pancreaticoduodenectomy were treated from January,2012 to December,2014, QiLu Hospital of Shandong University. They were performed by whether preoperative bilirubin levels are less than 171umol/L on a voluntary basis.We collected the patients clinical features such as gender,age, liver function before operation and leave hospital, operation time, intraoperative blood loss, intraoperative blood transfusion amount, tumor size, tumor location, tumor pathology,practical first eating time after operation,drainage tube remove time, postoperation hospitalization time, complication rate for statistical and study analysis. To analyze the effect of Bilirubin Levels in Patients Undergoing Pancreaticoduodenectomy. To explore the preoperative bilirubin levels should be controlled. To guide the clinical application of preoperative biliary drainage.Results:All operations were successfully performed. No operative deaths occurred in either group. Two groups’ general information have no significant difference(P> 0.05). Volumes of infused blood and loss of blood, liver function before operation and leave hospital and operation time have no significant difference(P>0.05) also. Practical first eating time after operation,drainage tube remove time, postoperation hospitalization time and the incidence of postoperative complications in the less than 171umol/L group are significant(P<0.05) less than in another group.Conclusions:The incidence of postoperative complications in the preoperative serum bilirubin levels< 171 umol/L group are significantly less than preoperative bilirubin levels ≥ 171 umol/L group. The former is significantly superior to the latter in practical first eating time after operation,drainage tube remove time and postoperation hospitalization time. So we can take appropriate measures to control the preoperative bilirubin levels<171 umol/L. Preoperative biliary drainage is a safe and feasible treatment measures. But it should be carried out by experienced physicians in this area. PBD (preoperative biliary drainage) is worth popularizing clinically.